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Case Report

Carcinosarcoma: A Rare Tumour of the Ovary

Vishakha Kandalgaonkar, Junior Resident, Department of Obstetrics and Gynecology, NKP Salve Institute of Medical Sciences & LMC, Nagpur, Maharashtra 440019, India. , Varsha Kose1 , Vishakha Kandalgaonkar2

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Indian Journal of Obstetrics and Gynecology 7(1):p 112-116, Jan-Mar 2019. | DOI: DOI: http://dx.doi.org/10.21088/ijog.2321.1636.7119.20

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Abstract

Introduction: Ovarian carcinosarcoma is one of the lethal malignant tumours of the female genital system. It is extremely rare and represents 1% of all malignant ovarian tumours. It occurs most commonly in postmenopausal women with the incidence peak in sixth decade, with only 10% incidence in younger women. They are associated with an aggressive clinical course and overall poor prognosis. Case report: Our reported case was a 60 year old postmenopausal lady who presented to us with pain and mass in lower abdomen since 15 days. Physical examination revealed a huge non tender suprapubic mass of uterine size 24 weeks suspected to be of ovarian origin. Shewas investigated and radiological studies confirmed a lesion of approx. 13.6 x 14.3 x 15.3 cms arising probably arising from the ovary, with heterogenous enhancement. Staging laparotomy was done with maximum debulking of large ovarian mass followed by Total Abdominal Hysterectomy with bilateral salpingo-oophorectomy with infra colic omentectomy. Left ovary was totally replaced by growth. Right ovary was small atrophic. Histopathology revealed Malignant Mixed Mullerian Tumour (MMMT) of the ovary with positive peritoneal cytology. Conclusion: The poor prognosis associated with this rare disease emphasizes the need for collaborative prospective studies targeted to better understand the molecular changes of MMMT and the need to design new therapeutic regimens to improve patients’ survival.

Keywords: Malignant mixed Mullerian tumour; ovary; carcinosarcoma; staging laparotomy

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DOI: DOI: http://dx.doi.org/10.21088/ijog.2321.1636.7119.20

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