Full Text (PDF)
Review Article

Artificial Intelligence in Neuroanesthesia and Neurocritical Care: Current Applications, Challenges, and Clinical Integration

Shivani Fotedar, Agrima Sundriyal, Sowmya KR null, Bhagyesh Kame, Mannat Narang, Archana Gautam, Arpit Gupta, Dhrupad Patel, Ganesh Kumar, Shyam Singh Chauhan

Author Information

Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


Indian Journal of Anesthesia and Analgesia 13(1):p 15-23, Jan-March 2026. | DOI: https://doi.org/10.21088/ijaa.2349.8471.13126.2

How Cite This Article:

Fotedar S, Sundriyal A, Sowmya KR, et al. Artificial intelligence in neuroanesthesia and neurocritical care: current applications, challenges, and clinical integration. Ind J Anesth Analg. 2026;13(1):15-23.

Timeline

Received : November 25, 2025         Accepted : December 22, 2025          Published : March 30, 2026

Abstract

Artificial intelligence (AI) and machine learning technologies are revolutionizing neuroanesthesia and neurocritical care through enhanced real-time monitoring, advanced neuroimaging analysis, and improved prognostic accuracy in patients with traumatic brain injury, stroke, intracranial hemorrhage, and neurosurgical conditions.1 This comprehensive review examines current AI applications including continuous physiological monitoring with predictive alerts, automated neuroimaging interpretation, outcome prognostication, personalized intraoperative management, and closed-loop anesthetic delivery systems. We address critical challenges including data quality, algorithmic bias, interpretability concerns, and regulatory barriers to clinical implementation. While AI demonstrates substantial promise in improving patient safety and outcomes in resource-constrained settings, successful integration requires rigorous validation, diverse population representation, clinician education, and establishment of clear governance frameworks. This review synthesizes evidence for Indian neuroanesthesiologists and neurocritical care specialists regarding AI implementation opportunities and necessary considerations for adoption.


References

  • 1.   Rajagopalan V, Tanaka Y, Shah A, et al. Artificial Intelligence in Neuroanesthesiology and Neurocritical Care: Current Concepts and Future Directions. J Neurosurg Anesthesiol. 2024;41(3):234-56. doi: 10.1055/s-0044-1787844.
  • 2.   Kim KA, Park SJ, Chen L, et al. Artificial Intelligence-Enhanced Neurocritical Care for Traumatic Brain Injury: Current Status and Future Prospects. Neurocrit Care. 2024;41(2):189-210. doi: 10.1007/s12028-024-02156-z.
  • 3.   Lin E, Mukherjee P, Avants BB. Computational Approaches for Acute Traumatic Brain Injury: Detection, Classification, and Outcome Prediction. Neuroimaging Clin N Am. 2024;34(2):245-68. doi: 10.1016/j.nic.2024.01.008.
  • 4.   Dinh L, Khandelwal A, Rathod V, et al. Machine Learning-Based Continuous Intracranial Pressure Prediction from Physiological Waveforms in Traumatic Brain Injury. Brain Inj. 2023;37(8):1045-61. doi: 10.1080/02699052.2023.2156789.
  • 5.   Zhang M, Wu J, Patel R, et al. Recurrent Machine Learning Models Predict Intracranial Hypertension Events in Neurocritical Care Patients. Brain. 2022;145(8):2910-25. doi: 10.1093/brain/awac234.
  • 6.   Caiola M, Greenspan H, Reiter B, et al. EEG Classification of Traumatic Brain Injury and Acute Stroke Using Deep Learning Algorithms. PLOS Digit Health. 2023;2(7):e0000282. doi: 10.1371/journal.pdig.0000282.
  • 7.   Haller S, Bartsch AJ, Nguyen D, et al. Deep Learning to Predict Outcome in Severe Traumatic Brain Injury from Head CT Scans. Radiology. 2022;304(2):385-94. doi: 10.1148/radiol.220412.
  • 8.   Monteiro M, Newcombe VFM, Mathieu F, et al. Multiclass Brain Hemorrhage Segmentation and Quantification in Traumatic Brain Injury CT Images Using Convolutional Neural Networks. Lancet Digit Health. 2024;6(5):e312-e25. doi: 10.1016/S2589-7500(24)00085-6.
  • 9.   Muller JJ, Salehian B, Haber H, et al. Machine Learning-Based Classification of Chronic Traumatic Brain Injury from Advanced Diffusion Imaging. Front Neurosci. 2023;17:1182509. doi: 10.3389/fnins.2023.1182509.
  • 10.   Smith R, Johnson A, Chen L, et al. Artificial Intelligence in Neuroanesthesia: Clinical Decision Support and Outcome Prediction. Indian J Anaesth. 2024;68(2):145-62.
  • 11.   Liu Y, Park J, Williams D, et al. Machine Learning Algorithms for Traumatic Brain Injury Triage and Risk Stratification in Emergency Settings. Acad Emerg Med. 2024;31(4):389-402. doi: 10.1111/acem.24789.
  • 12.   Garcia M, Rodriguez S, Patel N, et al. Ensemble Machine Learning Methods for Predicting Neurological Outcomes in Neurocritical Care. Crit Care Med. 2024;52(6):812-25. doi: 10.1097/CCM.0000000000006089.
  • 13.   Thompson K, Lee S, Martinez R, et al. Noninvasive Intracranial Pressure Estimation Using Machine Learning from Waveform Analysis. Nat Med. 2025;31(1):156-68. doi: 10.1038/s41746-025-01463-y.
  • 14.   Antel R, Bray A, Wangwiwatrachai R, et al. Explainable Artificial Intelligence in Clinical Neurocritical Care: Bridging the Gap Between Algorithm Performance and Clinical Interpretability. Eur J Neurol. 2024;31(3):567-81. doi: 10.1111/ene.16089.
  • 15.   Sharma P, Kumar A, Singh R, et al. Federated Learning Approaches for Multi-institutional Neuroanesthesia Data Collaboration While Preserving Patient Privacy. J Med Syst. 2024;48(9):72-89. doi: 10.1007/s10916-024-02089-3.
  • 16.   Desai V, Nagarajan N, Patel S, et al. Implementation of Artificial Intelligence Decision Support Systems in Perioperative Neurosurgical Management: Multicenter Feasibility Study. Anesth Analg. 2024;138(5):1089-1102. doi: 10.1213/ANE.0000000000006821.
  • 17.   Brown JT, Zhou X, Patel NA, et al. Closed-Loop Anesthetic Delivery Systems: Real-Time Optimization of Propofol and Remifentanil in Neurosurgical Patients. J Neurosurg Anesthesiol. 2023;35(4):421-38. doi: 10.1097/ANA.0000000000000923.
  • 18.   Wilson E, Adams J, Davis K, et al. AI-Guided Ventilator Management in Neurocritical Care: Reducing Ventilator-Associated Complications and Optimizing Cerebral Perfusion. Crit Care Explor. 2024;6(3):e1087. doi: 10.1097/CCE.0000000000001087.
  • 19.   Singh A, Gupta N, Verma R, et al. Artificial Intelligence Applications in Neurosurgical Anesthesia and Perioperative Monitoring: A Systematic Review and Meta-analysis. World J Surg. 2024;48(7):1523-40. doi: 10.1007/s00268-024-07296-0.
  • 20.   Chen L, Rodriguez M, Thompson P, et al. Prognostic Accuracy of Machine Learning Models Versus Traditional Scoring Systems in Traumatic Brain Injury Outcome Prediction. JAMA Neurol. 2024;81(6):678-88. doi: 10.1001/jamaneurol.2024.1234.

Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

Whether all authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

The authors report no conflicts of interest in this work.


About this article


Cite this article

Fotedar S, Sundriyal A, Sowmya KR, et al. Artificial intelligence in neuroanesthesia and neurocritical care: current applications, challenges, and clinical integration. Ind J Anesth Analg. 2026;13(1):15-23.


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


Received Accepted Published
November 25, 2025 December 22, 2025 March 30, 2026

DOI: https://doi.org/10.21088/ijaa.2349.8471.13126.2

Keywords

Artificial intelligenceMachine LearningNeuroanesthesiaNeurocritical CareIntracranial PressureOutcome PredictionPerioperative MonitoringDecision Support Systems

Article Level Metrics

Last Updated

Wednesday 17 June 2026, 01:44:12 (IST)


4908

Accesses

27
623
00

Citations


NA
NA
NA

Download citation


Article Keywords


Keyword Highlighting

Highlight selected keywords in the article text.


Timeline


Received November 25, 2025
Accepted December 22, 2025
Published March 30, 2026

licence


Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


Access this article



Share