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Analysis of Cervico- Vaginal Lesions in Women using Pap Smear: A Histopathological Study

Rashmi Chandragouda Meti, Associate Professor, Department of Microbiology, Kamineni Institute of Medical Sciences, Narketpalli, Nalgonda, Telangana 508254, India. , Anand Nagalikar1 , Rashmi Chandragouda Meti2

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Indian Journal of Pathology: Research and Practice 7(6):p 723-726, June 2018. | DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.7618.1

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Abstract

Background: Cervical cancer is one of the leading cancers in women. The confirmation of the disorder can be possible by Pap smear. The present study was conducted to assess the cases of cervical cancer in women using cervical Pap smear. 

Materials & Methods: This study was conducted in the Department of Pathology, ESIC Medical College, Gulburga, Karnataka (India) on 1080 cervico-vaginal smears which were checked for the epithelial abnormalities such as atypical squamous cells of uncertain significance (ASCUS), low-grade squamous intraepithelial lesion (LSIL), non neoplastic intraepithelial lesion (NILM), high-grade squamous intraepithelial lesion (HSIL) and squamous cell carcinoma (SCC). Results: Among 1080 Pap smears, 35 were unsatisfactory, 990 were NILM, 32 were LSIL, 10 were HSIL, 5 were SCC and 8 were ASCUS. The difference was significant (0.01). 1 case of ASCUS, 2 cases of LSIL were seen in age group 31-40 years. 2 cases of ASCUS, 3 cases of LSIL and 1 case of HSIL was seen in age group 41-50 years, 2 cases of ASCUS, 22 cases of LSIL, 6 cases of HSIL were seen in age group 51-60 years, 5 cases of LSIL, 3 cases of were seen in age group 61-70 years. 3 cases of ASCUS were seen in age group 71-80 years. The difference was significant (P- 0.01). The various changes were atrophy (30), non-specific inflammation (55), trichomoniasis (10), candidiasis (25), reactive (25), no other changes (840) and bacterial vaginosis (5). The difference was significant (P- 0.01). Conclusion: Cervical cancer is one of the leading cause of death in women. Pap smear is considered to be effective in detection of lesions in women. It is economical and non sophisticated procedure. Careful Pap smear analysis can be proved beneficial in preventing lesions.

Keywords: Cervical Cancer; Smear; Trichomoniasis.

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DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.7618.1

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