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Analysis of Cervical Pap Smears and Its Utilty in Screening for Premalignant Lesions in a Tertiary Care Instituition

Usha M.* , Usha M.* , Sharon Reginald** , Sharath Soman** , Rakshitha H.B.** , Avnika Jasuja** , Aneesha Asok**

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Indian Journal of Pathology: Research and Practice 6(1):p 17-21, January - March 2017. | DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.6117.3

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Abstract

 Introduction: Cervical cancer is the leading cause of mortality and morbidity among women with nearly four lakh new cases diagnosed annually worldwide, of which 80 % cases are in developing nations. Cervical Pap smear is a sensitive test for early screening of cervical lesions. Materials and Methods: A two year retrospective study of pap smears was conducted in the Department of Pathology from December 2013 – December 2015. A total of 5,464 pap smears were studied from patients in the age group of 17 ­80 years. Conventional pap smears were prepared according to standard procedures and were reported according to 2014 Bethesda system. Result: Out of 5,464 patients screened, 5,158(94.39 %) cases were benign, 157 (2.87%) were pre­malignant, 8 (0.14%) were malignant and 141 (2.58%) were unsatisfactory. The pre­malignant lesions were highest between 41­50 years and malignant cases between 51­60 years. Conclusion: Pap smear screening for cervical cancer is a highly effective tool for early detection of cervical premalignant lesions to prevent their progression to overt malignancy. Pap smear screening must be made mandatory after 30 years of age.

Keywords: Pap Smear; Screening; Intraepithelial Malignant Lesions.

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DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.6117.3

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