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A Triple Correlation Study - Fine Needle Aspiration Cytology and Imprint Cytology of Lymph node with Histopathological Examination

Anbumozhi M.K. Assistant Professo., Department of Pathology, Sree Balaji Medical College and Hospital, Chrompet, Chennai, Tamil Nadu 600044, India. , Anbumozhi M.K.1 , Bheema Rao2

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Indian Journal of Pathology: Research and Practice 7(4):p 453-461, April 2018. | DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.7418.8

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Abstract

Introduction:Lymphadenopathy is a term meaning disease of the lymph nodes . It is, however, almost synonymously used with swollen or enlarged lymph nodes due to infection, auto-immune disease or malignancy. FNAC and imprint is a valuable adjunct inprior to the histological diagnosis of lymphadenopathy.

Aim of the Study is to evaluate the diagnostic accuracy and efficacy of fine needle aspiration cytology and imprint cytology study in correlation with histopathological study.

Materials and Methods: was carried out in the department of Pathology, sreebalaji medical college and hospital, chrompet, chennai. 120 Fine needle aspiration cytology (FNAC) and corresponding imprint cytology prior to histopathology were studied in 53 cases.

Results: A total of 120 FNAC for lymphnode enlargement were done which revealed higher incidence of non neoplastic lesions 85% (102 cases) in comparison to neoplastic lesions 15% (18 cases),62 cases were males and 58 cases were females Out of 120 cases that underwent FNAC, excision biopsy was received in 53 cases, in which imprint was made from all 53 biopsy prior to HPE diagnosis which included 66.03% (35 cases) of benign lesions and 15% (18 cases) of malignant lesions.

Conclusion: FNAC cytology for suspicious palpable lymph nodes can be one of the first procedures performed during the patients work up as it could differentiate the infectious process from the neoplastic one, for mainly avoiding unnecessary surgery. Imprint is an reliable, rapid, and inexpensive tool in diagnosis of various lymph node diseases while awaiting histopathology report.

Keywords: FNAC; LN; HP. 


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DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.7418.8

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