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A Study to Determine the Role of Early Vitrectomy vs Intravitreal Antibiotics in Patients with Postoperative Endophthalmitis

Dr. Vinod Kumar Singh , Deepak Sharma1 , Pranav Saluja2 , Satya Prakash Singh3 , Kamaljeet Singh4 , Vinod Kumar Singh5 , Khushboo Meena6

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Ophthalmology and Allied Sciences 6(1):p 59-64, January-April 2020. | DOI: http://dx.doi.org/10.21088/oas.2454.7816.6120.9

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Deepak Sharma, Pranav Saluja, Satya Prakash, et al. A Study to Determine the Role of Early Vitrectomy vs Intravitreal Antibiotics
in Patients with Postoperative Endophthalmitis. Ophthalmol Allied Sci. 2020;6(1):59–64.

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Received : N/A         Accepted : N/A          Published : N/A

Abstract

 

Aim: To determine the role of early vitrectomy versus intravitreal antibiotic injection in patients with postoperative endophthalmitis. Design: Randomized, prospective study. Material and methods: A total of 20 patients who had clinical evidence of endophthalmitis within 6 weeks after cataract surgery were included in the study. Patients
were randomized into two groups. In Group A (n = 7) patients underwent core vitrectomy along with intravitreal antibiotics injection within 48 hours of presentation while in Group B (n = 13) patients received intavitreal antibiotic injection only. Results: In Group A (n = 7), all the patients had improvement in visual acuity. Out of total 7 patients,
5 (71.42%) patients achieved visual acuity of 6/60 or better, while in Group B (n = 13), 5 (38.46%) patients had improvement in visual acuity, 3 (30.76%) patients did not show any improvement or worsening and 5 (38.46%) patients had worsening of initial visual acuity. The media clarity improved significantly in all the patients of Group A (n = 7), in which 6 (85.71%) patients achieved the media clarity of Grade 1, while in Group B (n = 13) 6 (46.15%) patients achieved media clarity of Grade 1 and 2 (15.38%) patients did not have any improvement in media clarity during the follow-up period of 3 months. The complications were more in Group B as 2 (15.38%) patients developed retinal detachment, 1 (7.69%) patient had phthisis and 1(7.69%) patient worsened to panophthalmitis while in Group A only 1 (14.28%) patient developed retinal detachment 2 months after the vitrectomy. Conclusion: Early
vitrectomy when done within 48 hours greatly improves visual acuity and media clarity when compared with intravitreal antibiotics injection alone.
Keywords: Postoperative endophthalmitis; Early vitrectomy and intravitreal antibiotics.

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Cite this article

 

Deepak Sharma, Pranav Saluja, Satya Prakash, et al. A Study to Determine the Role of Early Vitrectomy vs Intravitreal Antibiotics
in Patients with Postoperative Endophthalmitis. Ophthalmol Allied Sci. 2020;6(1):59–64.

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DOI: http://dx.doi.org/10.21088/oas.2454.7816.6120.9

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