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A Study on Correlation of Renal and Liver Function Test Parameters with Platelet Counts in Dengue Viral Infection: A Prospective Study

Perada Vasavi , Perada Vasavi1 , Vidya Kedarisetti2

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Indian Journal of Pathology: Research and Practice 9(2 (Part-1)):p 67-71, May-August 2020. | DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.9220.11

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Perada Vasavi, Vidya Kedarisetti. A Study on Correlation of Renal and Liver Function Test Parameters with Platelet Counts in Dengue Viral Infection: A Prospective Study. Indian J Pathol Res Pract 2020;9 (2 Part I):67–71.
 

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Received : N/A         Accepted : N/A          Published : N/A

Abstract

Introduction: Dengue is an arbo-viral disease of tropical areas. WHO estimates almost half the world’s population lives in countries where dengue infection is endemic. Various parameters have been used for assessing the severity, platelet are one such important predictors. Liver and kidney function abnormalities has also been noted in some patients.
Aims and Objectives: The present study aims to analyze the platelet counts and biochemical abnormalities of liver and renal involvement in dengue patients, also to see the correlation between platelet counts and LFT, RFT in predicting the disease course. Materials and Methods: A total number of 102 cases positive for Dengue NS1/ Ig M antibodies were included in the study from department of pathology, MNR Medical College over a period of 10 months from March 2019 to December 2019. Blood counts, LFT and RFT were evaluated. Statistical analysis with p value of less than 0.05 was considered significant. Results: A total of 102 confirmed cases of dengue were studied for various parameters. Patients from 15 years to 70 years of age with m:f ratio of 1.5:1, showed elevated Liver and renal function test parameters.
Conclusion: Alteration in AST, ALT levels was seen in all the cases. Renal function tests were elevated in only few people. Correlation between platelets count and LFT, RFT parameters showed inverse relation with statistical significance. Hence, these parameters can be utilized for monitoring the course of the disease.

Keywords: Biochemical abnormalities; Dengue; Platelet counts; Predictors of course.
 

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Perada Vasavi, Vidya Kedarisetti. A Study on Correlation of Renal and Liver Function Test Parameters with Platelet Counts in Dengue Viral Infection: A Prospective Study. Indian J Pathol Res Pract 2020;9 (2 Part I):67–71.
 

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DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.9220.11

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