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A Study of Histopathological Analysis of Endometrium in Abnormal Uterine Bleeding in a Tertiary Care Centre

Kalaivani Amitkumar , R. Aruna Geethanjali1 , Kalaivani Amitkumar2 , CD. Anand3 , Shivashekar Ganapathy4

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Indian Journal of Pathology: Research and Practice 8(2):p 199-204, March-April 2019. | DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.8219.12

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R. Aruna Geethanjali, Kalaivani Amitkumar, C D. Anand et al. A Study of Histopathological Analysis of Endometrium in
Abnormal Uterine Bleeding in a Tertiary Care Centre. Indian J Pathol Res Pract. 2019;8(2):199-204.
 

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Received : N/A         Accepted : N/A          Published : N/A

Abstract

 Context: Abnormal uterine bleeding (AUB) is an important clinical entity in females. Aims: The objective of the study was to study the histopathological (HPE) features of endometrium and to correlate its incidence with age factor in patients presenting with history of AUB. Settings and Design: Methods and Material: 198 endometrial curetting and 2 endometrial biopsies were included. Samples that are autolysed and inadequate were excluded. Histopathological patterns were studied with Haematoxylin and Eosin (H&E) staining. Statistical analysis used: Association between various histopathological patterns with age were assessed using chi square test. Results: Maximum cases of AUB were in the perimenopausal women. The most common cause of AUB was cyclical endometrium followed by hyperplasia without atypia. Histopathological patterns significantly correlated with age factors in our study. Conclusions: Our study provides specific stratification of patients with AUB based on many new differentials (compared to conventional approach) that would allow for specific treatment options and thereby improve quality of life for the patients.

Keywords: Abnormal Uterine Bleeding; Perimenopausal; Endometrium; Hyperplasia.

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R. Aruna Geethanjali, Kalaivani Amitkumar, C D. Anand et al. A Study of Histopathological Analysis of Endometrium in
Abnormal Uterine Bleeding in a Tertiary Care Centre. Indian J Pathol Res Pract. 2019;8(2):199-204.
 

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DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.8219.12

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