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A Brief Overview on Nipah Virus: A Bat Born Disease

Thumuganti Spandhana, Rahela Lubna, Sravanthi Gandu

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Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.

Journal of Pharmaceutical and Medicinal Chemistry 10(2):p 63-76, July - Dec 2024. | DOI: https://doi.org/10.21088/jpmc.2395.6615.10224.4

How Cite This Article:

Thumuganti Spandana, Rahela Lubna, Sravanthi Gandu. A Brief Overview on Nipah Virus: A Bat Born Disease. J Pharmaceut Med Chem. 2024;10(2): 63-76.

Timeline

Received : August 17, 2024         Accepted : November 11, 2024          Published : December 25, 2024

Abstract

Nipah virus is a newly formed Zoonosis. Which causes significant mortality in human & causes impact on public health. According to WHO for animal health Niv is a notifiable disease important to international trades. Niv belongs to the family paramyxoviridae and is related to Hendra virus. Nipah virus is a single- Negative (-ve) standard RNA and its size range is from (40 – 1900nm) the presence of reticular cytoplasmic inclusion near to the endoplasmic reticulum distinguish the virus from paramyxoviruses. Fruit bats are identified as the natural reservoir host. Electron micro graph shows Nipah virus particles (purple) & Infected Vero cell shows (Brown). It is started from the state of Malaysia, Singapore & later in India, Kerala etc. Niv spreads from direct contact with infected animals like bats, pigs & their body fluids like Blood, urine, saliva & food products contamination by body fluids of animals. Niv common symptoms are fever, cold, headache respiratory problems etc. PCR & ELISA are the methods for diagnosis purpose. There is no specific medication or vaccine for the treatment of Nipah virus. Currently several clinical trials on vaccines are going on including mRNA – based vaccines. There is a lack of vaccine & therapeutic to cure this disease. Supportive medication used for the treatment of symptoms are Acetaminophen or ibuprofen, Dimenhydrinate or ondansetron, Dextromethorphan, ipratropium, or salbutamol.

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Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

No conflicts of interest in this work.

About this article

Cite this article

Thumuganti Spandana, Rahela Lubna, Sravanthi Gandu. A Brief Overview on Nipah Virus: A Bat Born Disease. J Pharmaceut Med Chem. 2024;10(2): 63-76.

Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.

Received Accepted Published
August 17, 2024 November 11, 2024 December 25, 2024
DOI: https://doi.org/10.21088/jpmc.2395.6615.10224.4

Keywords

Nipah virusparamyxoviridaePCR & ELISAzoonotic virusEncephalitis

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Timeline

Received August 17, 2024
Accepted November 11, 2024
Published December 25, 2024

licence

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


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