Ravi Kumar Chittoria Senior Professor and Associate Dean (Academic), Head of IT Wing and Telemedicine, Department of Plastic Surgery and Telemedicine, JIPMER, Pondicherry 605006, India
Karthikeyan null Junior Resident, Department of Orthopaedic Surgery, JIPMER, Puducherry 605006, India
Jacob Antony Chakiath Senior Resident, Department of Plastic Surgery, JIPMER, Puducherry 605006, India
Kanav Gupta Senior Resident, Department of Plastic Surgery, JIPMER, Puducherry 605006, India
Address for correspondence: Ravi Kumar Chittoria, Senior Professor and Associate Dean (Academic), Head of IT Wing and Telemedicine, Department of Plastic Surgery and Telemedicine, JIPMER, Pondicherry 605006, India E-mail: drchittoria@yahoo.com
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Journal of Dermatology
9(2):p 61-64, July-December 2024. | DOI: na
How Cite This Article:
Karthikeyan, Ravi Kumar Chittoria, et al., Utilizing Collagen and Dermal Matrix Extract Scaffold: Effective Regenerative Therapy for Burn Injuries. RFP Jr of Drea 2024;9(2):61-64.
Timeline
Received : September 20, 2024
Accepted : November 13, 2024
Published : December 25, 2024
Abstract
Tangential excision followed by immediate coverage using split skin grafts is considered the standard approach for treating deep burns, but it comes with its drawbacks. Challenges arise when there’s a lack of donor area, and the grafts often lead to contraction and suboptimal aesthetic and functional results. While various biological and cellular substitutes have been developed, they tend to be costly and not always suitable for routine use in our demographic. Here, we present a new technique utilizing a collagen and dermal extract scaffold from full thickness skin graft (Fig. 3) obtained from abdominoplasty (Fig. 2) of the same patient for wound coverage. This scaffold offers safety, ease of preparation, affordability, and effectiveness in managing raw areas post-procedure.
References
1. Shahrokhi S., Anna A., Jeschke M. The use of dermal substitutes in burn surgery: Acute phase. Wound Repair Regen. 2014 Jan-Feb; 22(1):14-22.
2. Divya Sree D, Saranya D. Artificial skin scaffold to Fig. 3: Postoperative photograph taken on POD 5 showing contracted healed wounds with minimal raw area with multiple small epithelial islands. Fig. 1: Pre-operative photograph showing post burn raw area over back and gluteal region Fig. 2: Intra- operative photograph showing dermal extract and collagen scaffold Agrawal L., Sudhanva H.K., Preethitha B. et. al. / Role of Dermal Extract and Collagen Scaffold in Management of Post Burns Raw Area 242 New Indian Journal of Surgery / Volume 9 Number 2 / March - April 2018 treat burn scars and its other applications. IJPBS 2015 Apr-Jun; 5(2):11-24.
3. Yannas I.V., Burke J.F. Design of an artificial skin. I. Basic design principles. J. Biomed Mater Res. 1980; 14(1):65–81.
4. Ryssel H., Gazyakan E., Germann G., Ohlbauer M. The use of MatriDerm in early excision and simultaneous autologous skin grafting in burnsa pilot study. Burns 2008 Feb; 34(1):93-7. Epub 2007 Jul 17.
5. Lineen E., Namias N., Biologic dressing in burns. J. Craniofac Surg. 2008 Jul; 19(4):923-8.
6. Mathangi R.K., Babu M., Mathivanan, Jayaraman V., Shankar J. Advantages of collagen based biological dressings in the management of superficial and superficial partial thickness burns in children. Ann Burns Fire Disasters. 2013 Jan 30;26(2):98-104.
Data Sharing Statement
There are no additional data available. All raw data and code are available upon request.
Funding
This research received no funding.
Author Contributions
All authors contributed significantly to the work and approve its publication.
Ethics Declaration
This article does not involve any human or animal subjects, and therefore does not require ethics approval.
Acknowledgements
We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.
Conflicts of Interest
No conflicts of interest in this work.
About this article
Cite this article
Karthikeyan, Ravi Kumar Chittoria, et al., Utilizing Collagen and Dermal Matrix Extract Scaffold: Effective Regenerative Therapy for Burn Injuries. RFP Jr of Drea 2024;9(2):61-64.
This license enables
reusers to distribute, remix, adapt, and build upon the material in any medium
or format for noncommercial purposes only, and only so long as attribution is
given to the creator.
This license enables
reusers to distribute, remix, adapt, and build upon the material in any medium
or format for noncommercial purposes only, and only so long as attribution is
given to the creator.