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Utilizing Collagen and Dermal Matrix Extract Scaffold: Effective Regenerative Therapy for Burn Injuries

Ravi Kumar Chittoria, Karthikeyan null, Jacob Antony Chakiath, Kanav Gupta

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Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

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Journal of Dermatology 9(2):p 61-64, July-December 2024. | DOI: na

How Cite This Article:

Karthikeyan, Ravi Kumar Chittoria, et al., Utilizing Collagen and Dermal Matrix Extract Scaffold: Effective Regenerative Therapy for Burn Injuries. RFP Jr of Drea 2024;9(2):61-64.

Timeline

Received : September 20, 2024         Accepted : November 13, 2024          Published : December 25, 2024

Abstract

Tangential excision followed by immediate coverage using split skin grafts is considered the standard approach for treating deep burns, but it comes with its drawbacks. Challenges arise when there’s a lack of donor area, and the grafts often lead to contraction and suboptimal aesthetic and functional results. While various biological and cellular substitutes have been developed, they tend to be costly and not always suitable for routine use in our demographic. Here, we present a new technique utilizing a collagen and dermal extract scaffold from full thickness skin graft (Fig. 3) obtained from abdominoplasty (Fig. 2) of the same patient for wound coverage. This scaffold offers safety, ease of preparation, affordability, and effectiveness in managing raw areas post-procedure.


References

  • 1.   Shahrokhi S., Anna A., Jeschke M. The use of dermal substitutes in burn surgery: Acute phase. Wound Repair Regen. 2014 Jan-Feb; 22(1):14-22.
  • 2.   Divya Sree D, Saranya D. Artificial skin scaffold to Fig. 3: Postoperative photograph taken on POD 5 showing contracted healed wounds with minimal raw area with multiple small epithelial islands. Fig. 1: Pre-operative photograph showing post burn raw area over back and gluteal region Fig. 2: Intra- operative photograph showing dermal extract and collagen scaffold Agrawal L., Sudhanva H.K., Preethitha B. et. al. / Role of Dermal Extract and Collagen Scaffold in Management of Post Burns Raw Area 242 New Indian Journal of Surgery / Volume 9 Number 2 / March - April 2018 treat burn scars and its other applications. IJPBS 2015 Apr-Jun; 5(2):11-24.
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Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

No conflicts of interest in this work.


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Cite this article

Karthikeyan, Ravi Kumar Chittoria, et al., Utilizing Collagen and Dermal Matrix Extract Scaffold: Effective Regenerative Therapy for Burn Injuries. RFP Jr of Drea 2024;9(2):61-64.


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


Received Accepted Published
September 20, 2024 November 13, 2024 December 25, 2024

DOI: na

Keywords

Dermal matrix scoffoldingRegenerative therapyThermal burnsWound healing

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Timeline


Received September 20, 2024
Accepted November 13, 2024
Published December 25, 2024

licence


Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


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