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Case Report

Pachydermoperiostosis, Complete Form: A Case Report of Rare Occurrence

Sunanda Arun Mahajan, Ketki Shekhar Bhoite, Siddhi Rajesh Patadia

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Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

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Journal of Dermatology 10(2):p 59-62, July-December 2025. | DOI: https://doi.org/10.21088/jd.2582.3582 10225.3

How Cite This Article:

Ketki Shekhar Bhoite, Siddhi Rajesh Patadia, Sunanda Arun Mahajan, et al. Pachydermoperiostosis, Complete Form: A Case report of Rare Occurrence. RFP Jr of Drea 2025; 10(2): 59-62.

Timeline

Received : May 22, 2025         Accepted : September 27, 2025          Published : December 25, 2025

Abstract

Pachydermoperiostosis is a rare genetic disorder featuring a triad of pachydermia, periostosis and digital clubbing. It is either caused by the mutations in the HPGD (AR inheritance) or SLCO2A1 gene (AD inheritance), resulting in elevated prostaglandins E2 levels. It can be classified on the basis of presence or absence of underlying cardiac, pulmonary or hepatic disease as primary or secondary. We hereby report a case of complete form of primary pachydermoperiostosis.

References

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Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

No conflicts of interest in this work.

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Cite this article

Ketki Shekhar Bhoite, Siddhi Rajesh Patadia, Sunanda Arun Mahajan, et al. Pachydermoperiostosis, Complete Form: A Case report of Rare Occurrence. RFP Jr of Drea 2025; 10(2): 59-62.

Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.

Received Accepted Published
May 22, 2025 September 27, 2025 December 25, 2025
DOI: https://doi.org/10.21088/jd.2582.3582 10225.3

Keywords

PachydermiaPeriostosisHypertrophic Osteoarthropathy

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Timeline

Received May 22, 2025
Accepted September 27, 2025
Published December 25, 2025

licence

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


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