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Unfolding the Impact of Artificial Sweetners on Gut Microbiome Leading to Metabolic Disease: Obesity & Diabetes Mellitus

Nancy Sahni, , Nancy Sahni1 , Urvashi Rana2

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International Journal of Food, Nutrition & Dietetics 12(3):p 154-162, September - December 2024. | DOI: http://dx.doi.org/10.21088/ijfnd.2322.0775.12324.7

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Nancy Sahni, Urvashi Rana, Unfolding the Impact of Artificial Sweetners on Gut Microbiome Leading to Metabolic Disease: Obesity & Diabetes Mellitus. Int J Food Nutr Diet. 2024;12(3):154-162.
 

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Abstract

Artificial sweeteners (AS) are in high demand due to their low-calorie content. They are used as sugar substitutes by diabetic and obese people, however current research indicates that NSS use may contribute to metabolic disorders. The FSSAI has cleared the use of six artificial sweeteners within acceptable amounts to improve tolerance and ensure safe use. However, many popular nutraceuticals and protein powders contain artificial sweeteners without mentioning how much are used, which may exceed the FSSAI’s limits at the expense of the consumer’s health.The health effects of these non-caloric sweeteners are still debated since they are metabolized differently, and their metabolic end products have been connected to gut microbiota, glucose intolerance, and weight gain. Although long-term human studies on artificial sweeteners are rare, an effort has been made to analyse previous evidence to consolidate the relation of AS with health issues.
 

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Cite this article

Nancy Sahni, Urvashi Rana, Unfolding the Impact of Artificial Sweetners on Gut Microbiome Leading to Metabolic Disease: Obesity & Diabetes Mellitus. Int J Food Nutr Diet. 2024;12(3):154-162.
 

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DOI: http://dx.doi.org/10.21088/ijfnd.2322.0775.12324.7

Keywords

Artificial sweeteners; Dysbiosis; Gut microbiome; Diabetes and metabolic diseases.

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