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To Study and Compare Efficacy of Ropivacaine and Bupivacaine for Caudal Analgesia in Paediatric Patients

Manish Kokne , Aishwarya Bandewar1 , Alok Kumar2 , Manish Kokne3

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Indian Journal of Anesthesia and Analgesia 6(1):p 197-206, Jan-Feb 2019. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.6119.28

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Aishwarya Bandewar, Alok Kumar, Manish Kokne. To Study and Compare Efficacy of Ropivacaine and Bupivacaine for Caudal Analgesia in Paediatric Patients. Indian J Anesth Analg. 2019;6(1):197-206.


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Abstract

Aims and objectives: The aim of the study was to compare quality and duration of intra and post operative analgesia and need of rescue analgesia of 0.5 ml/kg of 0.25% Bupivacaine. and 0.5 ml/kg of 0.2% Ropivacaine. Methodology: We conducted a prospective, randomized, double blind study, in which 60 paediatric patients undergoing lower abdominal and genitourinary surgeries. Group A received 0.5 ml/kg of 0.25% Bupivacaine and Group B received 0.5 ml/kg of 0.2% Ropivacaine. Quality and duration of motor block, Adjunct to general anaesthesia, Margin of safety of ropivacaine over Bupivacaine was assessed. Results: Both the drugs provided post-operative analgesiaMean duration of post-operative analgesia is 344.5±29.37 min in group A & that In group B is 346.3±10.66 min (paired) two tailed p value is 0.749 which is comparable & statistically not significant. Mean duration of motor block in group A is 176.6±21.02 min and in group B was 103.8±11.79 min with P value of 0.0001 which is statistically significant. The incidence of the side effect between the two groups is not statistically significant. Conclusion: Caudal block with 0.2% Ropivacaine resulted in equal duration of analgesia with less duration of motor block as compared with 0.25% caudal Bupivacaine, without an increase in incidence of side effects when administered pre-operatively in a volume of 0.5 ml/kg to children undergoing lower abdominal and urogenital surgeries.


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Aishwarya Bandewar, Alok Kumar, Manish Kokne. To Study and Compare Efficacy of Ropivacaine and Bupivacaine for Caudal Analgesia in Paediatric Patients. Indian J Anesth Analg. 2019;6(1):197-206.


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DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.6119.28

Keywords

Ropivacaine; Bupivacaine; Abdominal and urogenital surgeries.

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