Home > Journals > Indian Journal of Anesthesia and Analgesia

Indian Journal of Anesthesia and Analgesia

Submit your article Read this Journals View all journals
Full Text (PDF)
Original Article

To Evaluate the Hemodynamic Effects of Induction doses of Propofol and Etomidate under Entropy Guidance: A Prospective, Observational Study

Santpur Madhavi, Associate Professor, Department of Anaesthesia, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, Ambala, Haryana 133207, India. , Thakur J.R.1 , Santpur Madhavi2 , Kanwal Preet3 , Singh Kuldeep4 , Guleria Inderja5 , Anita6

Author Information

Licence:



Indian Journal of Anesthesia and Analgesia 5(10):p 1639-1645, Oct 2018. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.51018.9

How Cite This Article:

Timeline

Received : N/A         Accepted : N/A          Published : N/A

Abstract

  Context: Entropy monitoring enables us to administer the anaesthetic doses of induction agents with precision so as to avoid intraoperative awareness, light planes of anaesthesia on one hand and delayed recovery, haemodynamic instability on the other. Aims: To evaluate the haemodynamic effects of induction doses of propofol and etomidate under entropy guidance, in patients undergoing under general anaesthesia. Study design: A prospective, observational study. Methodology: This study was conducted on 100 patients of ASA I and II between the age group 18­60 years. The patients in group A, were induced with etomidate and group B, with propofol till entropy reached a value of 40. Haemodynamic parameters at and after induction were noted. Results: All statistical calculations were done using SPSS 21 version. The mean of mean arterial pressure at 1 minute after induction in group A and B was 85.9±10 and 75.5±8 respectively (p=0.00) and after laryngoscopy, in group A and B was 98.4±8.1 and 105.3±9.1 respectively (p=0.00). Significant rise in the heart rate was seen with propofol after laryngoscopy and intubation. (p=0.018) Conclusion: On induction doses under entropy guidance, the haemodynamic effects observed with propofol were more pronounced than that of etomidate. Propofol caused more hypotension than etomidate after induction, whereas, there was statistically significant rise in heart rate after laryngoscopy and intubation. 

References

No records found.


About this article

Cite this article

Licence:



Received Accepted Published
N/A N/A N/A
DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.51018.9

Keywords

Intravenous; Propofol; Etomidate; Induction; Haemodynamic Parameters; And Entropy.

Article Level Metrics

Last Updated

Monday 13 July 2026, 08:37:48 (IST)

5648

Accesses

5
678
00

Citations


NA
NA
NA

Download citation


Article Keywords

Keyword Highlighting

Highlight selected keywords in the article text.


Timeline

Received N/A
Accepted N/A
Published N/A

licence




Access this article

Reprint Order Form
Buy this Article
Institutional Subscriptions

Share