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Indian Journal of Anesthesia and Analgesia

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To Compare and Evaluate Hemodynamic Effect of Propofol and Etofol as Induction Agents in Elective Surgeries

Babita Ramdev, Associate Professor, Department of Anaesthesia, Maharishi Markandeshwar Institute of Medical Sciences and Research (MMIMSR), Mullana, Ambala, Haryana 133207, India , Manisha B. Dwivedi1 , Babita Ramdev2 , Harinder Singh3 , Dinesh Kumar Sharma4 , Inderja5 , Pranav Arora6 , Megha Singla7 , Heena Goyal8

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Indian Journal of Anesthesia and Analgesia 5(11):p 1835-1839, November-December 2018. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.51118.10

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Abstract

  Introduction: Various intravenous induction agents like propofol, ketamine and etomidate are available now a day to the anaesthetist but they also cause attenuation of axis leading to a decrease in heart rate and blood pressure. To achieve haemodynamic stability during induction is one of the major challenge and goal of the anaesthetist. Aims and objectives: To evaluate the hemodynamic effect of propofol and etofol as induction agents in elective surgeries under general anaesthesia . Material and Methodology: Sixty (60) ASA grade I and II patients of age group (18­60 years) were divided randomly into two study groups of thirty patients each, as follows: Group I­Propofol 2 mg/kg was given intravenously as induction agent Group II­Etofol (0.15mg/kg etomidate and 1mg/kg propofol) was given intravenously as induction agent. Results: In group II ( Etofol) lesser fall in haemodynamic parameters at induction and upto 60 minutes (p>0.05)of induction as compared to group I (Propofol). Conclusion: Etofol is more haemodynamically stable than propofol alone during induction. 

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DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.51118.10

Keywords

Propofol; Etomidate; Etofol; Haemodynamic; Induction

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