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Thyroid Cytology? The Bethesda System of Reporting to the Rescue!!

Raghav Kapoor, Adarsh Sanikop, Shubham Varshney, Aiusee Pooja

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Journal of Global Medical Education and Research 6(2):p 53-55, July-December 2023. | DOI: na

How Cite This Article:

Sanikop A, Kapoor R, Varshney S, et al. Thyroid cytology? The Bethesda System of reporting to the rescue!!. J Glob Med Educ Res. 2023;6(2):53-5.

Timeline

Received : July 19, 2023         Accepted : August 03, 2023          Published : September 30, 2023

Abstract

Introduction: The Bethesda system is a uniform reporting system for thyroid cytology that facilitates the clarity of communication among pathologists, and surgeons and facilitates cytohistologic correlation for thyroid diseases. An implied risk of malignancy, a preliminary triage, and at times a definitive diagnosis can be offered. Immunocy to chemistry can be done on cell blocks. Molecular studies can also be performed. Objective: This study was carried out to evaluate thyroid lesions by fine needle aspiration cytology (FNAC) based on Bethesda system of reporting. Materials and Methods: A total of 40 patients with clinically palpable thyroid lesions were studied at our institute between July 31, 2020, and December 31, 2020. FNAC was performed on those patients and slides were made, both air dried (MGG stained) and wet fixated (PAP, H & E stained). The slides were screen under light microscope and results were compared. Results: Based on the Bethesda system of classification of thyroid lesions, out of total 40 samples: 02 samples were diagnosed as non-diagnostic even after re-aspiration (Category 1). 21 lesions were diagnosed as benign (Category 2). 07 were in category of follicular lesion of undetermined significance (Category 3). 05 were diagnosed as suspicious for follicular neoplasm (Category 4). 03 as suspicious for malignancy (Category 5). 02 cases as malignant (Category 6). Conclusions: Reviewing the thyroid FNAs with the Bethesda system for reporting allowed precise cytological diagnosis. Nature of the disease, experience of pathologist, and understanding of certain limitations determine its diagnostic utility. Discussion: FNAC is a widely accepted method used in the diagnosis of patients with thyroid nodules. The lack of consistency in reporting FNA was solved in 2007, when TBSRTC was introduced.


References

  • 1.   Jo VY, Stelow EB, Dustin SM, Hanley KZ. Malignancy risk for fine-needle aspiration of thyroid lesions according to the Bethesda System for Reporting Thyroid Cytopathology. Am J Clin Pathol. 2010;134(3):450-6.
  • 2.   Hamberger B, Gharib H, Melton LJ 3rd, Goellner JR, Zinsmeister AR. Fine-needle aspiration biopsy of thyroid nodules: Impact on thyroid practice and cost of care. Am J Med. 1982;73(3):381-4.
  • 3.   Rosen Y, Rosenblatt P, Saltzman E. Intraoperative pathologic diagnosis of thyroid neoplasms. Cancer. 1990;66(9):2001-6.
  • 4.   Ali SZ, Cibas ES, editors. The Bethesda System for Reporting Thyroid Cytopathology: Definitions, Criteria, and Explanatory Notes. 2nd ed. New York: Springer; 2018.
  • 5.   Renshaw AA. Histologic follow-up of nondiagnostic thyroid fine needle aspirations: Implications for adequacy criteria. Diagn Cytopathol. 2012;40 Suppl 2:E13-5.
  • 6.   Vivero M, Renshaw AA, Krane JF. Adequacy criteria for thyroid FNA evaluated by ThinPrep slides only. Cancer Cytopathol. 2017;125(7):534-43.
  • 7.   Singh RS, Wang HH. Timing of repeat thyroid fine-needle aspiration in the management of thyroid nodules. Acta Cytol. 2011;55(6):544-8.
  • 8.   Lee HY, Baek JH, Yoo H, Kim JK, Lim MK, Chu YC, et al. Repeat fine-needle aspiration biopsy within a short interval does not increase the atypical cytologic results for thyroid nodules with previously nondiagnostic results. Acta Cytol. 2014;58(4):330-4.

Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

Whether all authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

The authors report no conflicts of interest in this work.


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Cite this article

Sanikop A, Kapoor R, Varshney S, et al. Thyroid cytology? The Bethesda System of reporting to the rescue!!. J Glob Med Educ Res. 2023;6(2):53-5.


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator



Received Accepted Published
July 19, 2023 August 03, 2023 September 30, 2023

DOI: na

Keywords

BethesdaFNAC (Fine Needle Aspiration CytologyThyroid

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Received July 19, 2023
Accepted August 03, 2023
Published September 30, 2023

licence


Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator



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