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Pediatric Education and Research 13(2 (Special Supplement -II)):p 394-396, July-Dec 2025. | DOI: https://doi.org/10.21088/per.2321.1644.13225.93
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The Contribution of Anne McLaren to the Field of Pediatric
Patil Sakshi Madhav, Kasumbiwal Ajay H., Lakhe Siddheshwar A., More Sudarshan
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Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
Pediatric Education and Research 13(2 (Special Supplement -II)):p 394-396, July-Dec 2025. | DOI: https://doi.org/10.21088/per.2321.1644.13225.93
How Cite This Article:
Kasumbiwal Ajay H., Lakhe Siddheshwar A., More Sudarshan, et al. The Contribution of Anne McLaren to the Field of Pediatric. Pediatr. Edu. Res. 2025; 13(2): 394-396.Timeline
Received : December 12, 2025
Accepted : December 25, 2025
Published : December 30, 2025
Abstract
Anne McLaren (1927–2007) was a pioneering British developmental biologist whose work laid the scientific foundations for modern reproductive biology and assisted reproductive technologies. Her research on mouse embryology clarified key mechanisms of early development, implantation, and embryo culture, leading to major advances in in vitro fertilization (IVF) and stem cell biology. McLaren’s collaborative work with John Biggers in 1958 demonstrated, for the first time, that mammalian embryos could be developed in vitro and result in live births after transfer an achievement that transformed reproductive science. Throughout her career, she contributed extensively to understanding germ cell development, genetic influences on embryogenesis, and the ethical implications of reproductive technologies. McLaren also played an influential role in policy, serving on the Warnock Committee, which shaped UK legislation on embryo research. Her scientific achievements and ethical leadership firmly establish her as one of the most important figures in modern developmental and reproductive biology.
References
- 1. McLaren, A. Reproduction in Mammals. Cambridge University Press; 1981.
- 2. McLaren, A. “The Embryo Project: Experimental Embryology in the 20th Century.” Development, 1989, 107 (Supplement), 1–13.
- 3. Johnson, M.H., & McLaren, A. . Mammalian Genetics and Fertility. Oxford University Press. 1990.
- 4. Johnson, M.H., & West, J.D. Anne McLaren. 26 April 1927 – 7 July 2007. Biographical Memoirs of Fellows of the Royal Society, 2009, 55, 219–256. (Available on the Royal Society website.)
- 5. The Embryo Project Encyclopedia (Arizona State University). Anne Laura Dorinthea McLaren (1927–2007).
- 6. Lovell-Badge, R. (2007). “Anne McLaren (1927–2007).” Nature, 448, 274.
- 7. BBC News – Obituary:“Dame Anne McLaren: Pioneer of IVF
Data Sharing Statement
There are no additional data available. All raw data and code are available upon request.
Funding
This research received no funding.
Author Contributions
All authors contributed significantly to the work and approve its publication.
Ethics Declaration
This article does not involve any human or animal subjects, and therefore does not require ethics approval.
Acknowledgements
We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.
Conflicts of Interest
No conflicts of interest in this work.
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Cite this article
Kasumbiwal Ajay H., Lakhe Siddheshwar A., More Sudarshan, et al. The Contribution of Anne McLaren to the Field of Pediatric. Pediatr. Edu. Res. 2025; 13(2): 394-396.
Licence:
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
| Received | Accepted | Published |
|---|---|---|
| December 12, 2025 | December 25, 2025 | December 30, 2025 |
DOI: https://doi.org/10.21088/per.2321.1644.13225.93
Keywords
Developmental BiologyEmbryologyIVFStem Cell ResearchGerm cell developmentImplantationSearch for Similar Articles
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Timeline
| Received | December 12, 2025 |
| Accepted | December 25, 2025 |
| Published | December 30, 2025 |
licence
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
