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RFP Journal of Dermatology

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Case Report

Successful Non-Surgical Treatment of Buschke-Lowenstein Tumour with 12 Weeks of 5% Imiquimod Alone

Sidharth Sonthalia, Consultant Dermatologist & Dermatosurgeon, Skinnocence: The Skin Clinic & Research Centre, Sushant Lok-1, Gurugram, Haryana 122002, India , Sonthalia Sidharth* , Vijay Gandhi**

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RFP Journal of Dermatology 2(2):p 71-73, Jul-Dec 2017. | DOI:

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Abstract

Buschke Lowenstein tumour (BLT), also known as giant condylomata acuminate is a rare locally invasive tumour. This cauliflower-like lesion of the anogenital region often arises from a pre-existing warty lesion. It is locally destructive despite a relatively benign appearance on histopathology. It carries a high recurrence rate and a significant potential for malignant transformation into verrucous squamous cell carcinoma. While wide surgical excision has been the mainstay of therapy, use of combination treatments is gaining ground. However, patient-specific issues and complications often render ideal treatment infeasible, with need for innovative approach to therapy. We report the case of a young Indian man with BLT with dysplastic changes, treated successfully with 16-week long monotherapy with 5% imiquimod cream, owing to unsuitability of traditional therapies in his case.

Keywords: Buschke Lowenstein; Genital Wart; Condylomata Lata; Squamous Cell Carcinoma; Imiquimod. 

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