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Study of Dexmedetomidine as an Adjuvant to Bupivacaine- Lignocaine with Adrenaline in Supraclavicular Brachial Plexusblock

Sandhya Gujar, Karuna Sidam

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Indian Journal of Anesthesia and Analgesia 10(3):p 85-95, July-September 2023. | DOI: https://doi.org/10.21088/ijaa.2349.8471.10323.1

How Cite This Article:

Sandhya Gujar, Karuna Sidam/Study of Dexmedetomidine as an Adjuvant to Bupivacaine-Lignocaine with Adrenaline in
Supraclavicular Brachial Plexusblock/Indian J Anesth Analg. 2023;10(3) 85-95.

Timeline

Received : May 02, 2023         Accepted : June 15, 2023          Published : August 30, 2023

Abstract

Supraclavicular brachial plexus block is a very popular mode of anesthesia for various upper limb surgeries, as it is easiest and most effective and has good post-operative analgesia. It is carried out at the level of trunks i.e7 at the middle of brachial plexus, resulting in homogenou spread of anesthetic agent throughout the plexus with a fast onset and complete block action.9 Dexmedetomidine, is potent, highly selective α2-adrenoceptor agonist, has been used as an adjuvant during regional and local anesthesia because of rapid onset of action and relatively short half-life up to 2 hours.

Objective of Study: To compare the effects of addition of Dexmedetomidine to Bupivacaine- Lignocaine with Adrenaline combination for Supraclavicular brachial plexus block with regards to onset and duration of sensory block, motor block. Quality of anesthesia, analgesia and Adverse reactions if any after taking written informed consent.

Observations: Onset of sensory as well as motor blockade in Dexmedetomidine group was earlier when compared to plain bupivacaine-lignocaine adrenalin group. The duration of sensory and motor blockade was significantly increased (p<0.05) in Dexmedetomidine group when compared to another group. With respect to hemodynamic parameters Dexmedetomidine group provided a higher Degree of cardiovascular stability with a lesser incidence of hypotension.

Result: There is earlier onset of action and longer duration of sensory; Motor block and Duration of analgesia (sensory block) was prolonged in dexmedetomidine group. Hence it is advisable to add dexmedetomidine as an adjuvant to local anesthetic combinations during supraclavicular block for prolonged anesthesia and to provide better analgesia


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Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

Information not provided.

Conflicts of Interest

The authors report no conflicts of interest in this work.


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Cite this article

Sandhya Gujar, Karuna Sidam/Study of Dexmedetomidine as an Adjuvant to Bupivacaine-Lignocaine with Adrenaline in
Supraclavicular Brachial Plexusblock/Indian J Anesth Analg. 2023;10(3) 85-95.


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


Received Accepted Published
May 02, 2023 June 15, 2023 August 30, 2023

DOI: https://doi.org/10.21088/ijaa.2349.8471.10323.1

Keywords

0.5% Bupivacaine2% lignocaine with adrenalineDexmedetomidinePeripheral nerve stimulator (stimuplex DIG RC)Sensory and motor blockade

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Received May 02, 2023
Accepted June 15, 2023
Published August 30, 2023

licence


Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


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