This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
Padmavathi R, Sethuraj P, Rathipriya PS. Studies on Genetic Control of Insects and Public Health Importance: A Survey. Indian J Genet Mol Res. 2023;12(1):13-30.
Timeline
Received : January 19, 2023
Accepted : February 25, 2023
Published : June 10, 2023
Abstract
During recent years many advances have been made in the development of insect control by genetic manipulation. These methods include the sterile male technique, now well known, which depends on ionizing radiation or chemo sterilization. The recent field experiment carried out by WHO in Rangoon, Burma, on Culex fatigans has demonstrated that naturally occurring cytogenetic mechanisms such as cytoplasmic incompatibility can be used successfully without the use of radiations or chemosterilants. The paper not only describes the experiment on Culex fatigans but also discusses basic concepts and theoretical considerations involved in genetic control of insects of public health importance. There are a number of problems which require study before genetic control can be used on an operational scale.
References
1. Sokolowski MB, Levine JD. Nature-nurture interactions. In: Szekely T, Moore AJ, Komdeur J, editors. Social Behaviour, Genes, Ecology and Evolution. Cambridge (UK): Cambridge University Press; 2010. p. 11-25.
2. Schneider J, Atallah J, Levine JD. Social structure and indirect genetic effects: Genetics of social behaviour. Biol Rev Camb Philos Soc. 2017 Aug;92(3):1027-38.
3. Moore AJ, Brodie ED III, Wolf JB. Interacting phenotypes and the evolutionary process: I. Direct and indirect genetic effects of social interactions. Evolution. 1997 Sep;51(5):1352-62.
4. Wolf JB, Brodie ED III, Cheverud JM, Moore AJ, Wade MJ. Evolutionary consequences of indirect genetic effects. Trends Ecol Evol. 1998 Feb;13(2):64-9.
5. Linksvayer TA. The molecular and evolutionary genetic implications of being truly social for social insects. Adv Insect Physiol. 2015;48:271-93.
6. Weitekamp CA, Libbrecht R, Keller L. Genetics and evolution of social behavior in insects. Annu Rev Genet. 2017 Nov 23;51:219-39.
7. Avalos A, Avalos P, Rehan SM, Toth AL, Johnson BR. Genomic regions influencing aggressive behavior in honey bees are defined by colony allele frequencies. Proc Natl Acad Sci U S A. 2020 Jul 14;117(28):17135-41.
8. Sokolowski MB. Social interactions in
9. Rooke R, Rasool A, Schneider J, Levine JD. Drosophila melanogaster behaviour changes in different social environments based on group size and density. Commun Biol. 2020 Jun 16;3(1):304.
10. Rittschof CC, Hughes KA. Advancing behavioural genomics by considering timescale. Nat Commun. 2018 Jan 26;9(1):489.
11. Carter MJ, Wilson AJ, Moore AJ, Royle NJ. The role of indirect genetic effects in the evolution of interacting reproductive behaviors in the burying beetle, Nicrophorus vespilloides. Ecol Evol. 2019 Jan;9(2):998-1009.
12. Kent C, Azanchi R, Smith B, Formosa A, Levine JD. Social context influences chemical communication in D. melanogaster males. Curr Biol. 2008 Sep 23;18(18):1384-9.
13. Saltz JB. Genetic composition of social groups influences male aggressive behaviour and fitness in natural genotypes of Drosophila melanogaster. Proc Biol Sci. 2013 Dec 22;280(1773):20131926.
14. Robinson GE, Grozinger CM, Whitfield CW. Sociogenomics: Social life in molecular terms. Nat Rev Genet. 2005 Apr;6(4):257-70.
15. Wilson EO. The Insect Societies. Cambridge (MA): Belknap Press; 1971.
16. Whitfield CW, Ben-Shahar Y, Oldroyd BP, Rodriguez-Zas SL, Robinson GE. Genomic dissection of behavioral maturation in the honey bee. Proc Natl Acad Sci U S A. 2006 Oct 24;103(43):16068-75.
17. Shpigler HY, Siegel AJ, Cashman CR, Sina S, Smith CR, Robinson GE. Behavioral, transcriptomic and epigenetic responses to social challenge in honey bees. Genes Brain Behav. 2017 Jul;16(6):579-91.
18. Vrontou E, Nilsen SP, Demir E, Kravitz EA, Dickson BJ. fruitless regulates aggression and dominance in Drosophila. Nat Neurosci. 2006 Dec;9(12):1469-71.
19. Steinhauer NA, Rennich K, Wilson ME, Caron DM, Lengerich EJ, Pettis J, et al. A national survey of managed honey bees 2012-2013 annual colony losses in the USA: Results from the Bee Informed Partnership. J Apic Res. 2014;53(1):1-18.
20. Calderone NW. Insect pollinated crops, insect pollinators and US agriculture: Trend analysis of aggregate data for the period 1992-2009. PLoS One. 2012 May 21;7(5):e37235. doi: 10.1371/journal.pone.0037235. PMID: 22629374.
21. Smith KM, Loh EH, Rostal MK, Zambrana-Torrelio CM, Mendiola L, Daszak P. Pathogens, pests, and economics: Drivers of honey bee colony declines and losses. EcoHealth. 2014 Dec;10(4):434-45.
22. Mullin CA, Frazier M, Frazier JL, Ashcraft S, Simonds R, van Engelsdorp D, et al. High levels of miticides and agrochemicals in North American apiaries: implications for honey bee health. PLoS One. 2010 Mar 23;5(3):e9754. doi: 10.1371/journal.pone.0009754. PMID: 20333298.
23. Johnson RM, Pollock HS, Berenbaum MR. Synergistic interactions between in-hive miticides in Apis mellifera. J Econ Entomol. 2009 Apr;102(2):474-9. PMID: 19449624.
24. Johnson RM, Dahlgren L, Siegfried BD, Ellis MD. Acaricide, fungicide and drug interactions in honey bees (Apis mellifera). PLoS One. 2013 Jan 30;8(1):e54092. doi: 10.1371/journal.pone.0054092. PMID: 23382869.
25. Sandrock C, Tanadini M, Tanadini LG, Fauser-Misslin A, Potts SG. Impact of chronic neonicotinoid exposure on honeybee colony performance and queen supersedure. PLoS One. 2014 Aug 1;9(8):e103592. doi: 10.1371/journal.pone.0103592. PMID: 25084279.
26. Henry M, Beguin M, Requier F, Rollin O, Odoux JF, Aupinel P, et al. A common pesticide decreases foraging success and survival in honey bees. Science. 2012 Apr 6;336(6079):348-50. doi: 10.1126/science.1215039. PMID: 22461498.
27. Decourtye A, Armengaud C, Renou M, Devillers J, Cluzeau S, Gauthier M, et al. Imidacloprid impairs memory and brain metabolism in the honeybee (Apis mellifera L.). Pestic Biochem Physiol. 2004 Jan;78(2):83-92.
28. Peterson LR, Carson PJ, Biggerstaff BJ, Custer B, Borchardt SM, Busch MP. Estimated cumulative incidence of West Nile virus infection in US adults, 1999-2010. Epidemiol Infect. 2013 Mar;141(3):591-5.
29. Nasci RS. Movement of Chikungunya virus into the western hemisphere. Emerg Infect Dis. 2014 Aug;20(8):1394-5. doi: 10.3201/eid2008.140333. PMID: 25061832.
30. Jones DG, editor. Piperonyl Butoxide: The Insecticide Synergist. San Diego (CA): Academic Press; 1998.
31. Zhong H, Latham M, Hester PG, Frommer RL, Brock C. Impact of naled on honey bee Apis mellifera L. survival and productivity: aerial ULV application using a flat-fan nozzle system. Arch Environ Contam Toxicol. 2003 Aug;45(2):216-20. PMID: 14565579.
32. Seeley TD. The Wisdom of the Hive: The Social Physiology of Honey Bee Colonies. Cambridge (MA): Harvard Univ. Press; 1995. 295 p.
33. Winston ML. The Biology of the Honey Bee. Cambridge (MA): Harvard University Press; 1991. 294 p.
34. Harrison JF. Caste-specific changes in honeybee flight capacity. Physiol Zool. 1986 Mar-Apr;59(2):175–87.
35. Harrison JF, Fewell JH. Environmental and genetic influences on metabolic rate in the honey bee, Apis mellifera. Comp Biochem Physiol Part A: Molec Integ Physiol. 2002 Oct;133(2):323–33.
36. Rothenbuhler WC. Genetics and breeding of the honey bee. Annu Rev Entomol. 1958;3:161-80.
37. Harpur BA, Minaei S, Kent CF, Zayed A. Management increases genetic diversity of honey bees via admixture. Molec Ecol. 2012 Sep;21(18):4414-21.
38. Giray T, Robinson GE. Effects of intracolony variability in behavioral development on plasticity of division of labor in honey bee colonies. Behav Ecol Sociobiol. 1994 Jul;35(1):13-20.
39. Huang ZY, Robinson GE. Honey bee colony integration: worker-worker interactions mediate hormonally regulated plasticity in division of labor. PNAS. 1992 Dec 15;89(24):11726-9. PMID: 1465390.
40. Abbott WS. A method of computing the effectiveness of an insecticide. J Econ Entomol. 1925;18:265.
41. Stevenson JH. The acute toxicity of unformulated pesticides to worker honey bees (Apis mellifera L). Plant Path. 1978 Mar;27(1):38-40.
42. Danka RG, Rinderer TE, Hellmich RL, Collins AM. Comparative toxicities of four topically applied insecticides to Africanized and European honey bees (Hymenoptera: Apidae). J Econ Entomol. 1986 Feb;79(1):18-21.
43. Elzen PJ, Elzen GW, Rubink W. Comparative susceptibility of European and African bee ecotypes to several insecticide classes. Southwestern Entomologist. 2003 Dec;28(4):255-60.
44. Laurino D, Manino A, Patetta A, Parparato M. Toxicity of neonicotinoid insecticides on different honey bee genotypes. Bull Insectol. 2013 Jun;66(1):119-26.
45. Suchail S, Guez D, Belzunces LP. Characteristics of imidacloprid toxicity in two Apis mellifera subspecies. Environ Toxicol Chem. 2000 Aug;19(8):1901-5.
46. Robertson JL, Preistler HK. Pesticide Bioassays with Arthopods. Boca Raton (FL): CRC Press; 1992. 127 p.
47. Decourtye A, Devillers J, Genecque E, Le Menach K, Budzinski H, Cluzeau S, et al. Comparative sublethal toxicity of nine pesticides on olfactory learning performances of the honeybee Apis mellifera. Arch Environ Contam Toxicol. 2005 Feb;48(2):242-50. PMID: 15750780.
48. Wu JY, Anelli CM, Sheppard WS. Sub-lethal effects of pesticide residues in brood comb on worker honey bee (Apis mellifera) development and longevity. PLoS One. 2011 Feb 23;6(2):e14720. doi: 10.1371/journal.pone.0014720. PMID: 21373182.
49. Scott JG. Cytochromes P450 and insecticide resistance. Insect Biochem Mol Biol. 1999 Sep;29(9):757-77. PMID: 10510498.
50. Rinkevich FD, Du Y, Dong K. Diversity and convergence of sodium channel mutations involved in resistance to pyrethroids. Pestic Biochem Physiol. 2013 Aug;106(3):93-100. PMID: 24019556.
51. Iwaasa T, Motoyama N, Ambrose JT, Roe M. Mechanism for the differential toxicity of neonicotinoid insecticides in the honey bee, Apis mellifera. Crop Protect. 2004 Apr;23(4):371-8.
53. Tomizawa M, Casida JE. Neonicotinoid insecticide toxicology: mechanisms of selective action. Annu Rev Pharmacol Toxicol. 2005;45:247-68. PMID: 15822177.
54. Jones AK, Raymond-Delpech V, Thany SH, Gauthier M, Sattelle DB. The nicotinic acetylcholine receptor gene family of the honey bee, Apis mellifera. Genome Res. 2006 Nov;16(11):1422-30. PMID: 17065616.
55. Liu Z, Williamson MS, Lansdell SJ, Denholm I, Han Z, Millar NS. A nicotinic acetylcholine receptor mutation conferring target-site resistance to imidacloprid in Nilaparvata lugens (brown planthopper). Proc Natl Acad Sci U S A. 2005 Jun 14;102(24):8420-5. PMID: 15937112.
56. Rinkevich FD, Scott JG. Reduction of dADAR activity affects the sensitivity of Drosophila melanogaster to spinosad and imidacloprid. Pesticide Biochemistry and Physiology. 2012 Nov;104(3):163-9.
57. Johnson RM, Wen Z, Schuler MA, Berenbaum MR. Mediation of pyrethroid insecticide toxicity to honey bees (Hymenoptera: Apidae) by cytochrome P450 monooxygenases. J Econ Entomol. 2006 Aug;99(4):1046-50. PMID: 16937654.
58. Mao W, Schuler MA, Berenbaum MR. CYP9Q-mediated detoxification of acaricides in the honey bee (Apis mellifera). Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12657-62.
59. Claudianos C, Ranson H, Johnson RM, Biswas S, Schuler MA, Berenbaum MR, et al. A deficit of detoxification enzymes: pesticide sensitivity and environmental response in the honeybee. Insect Mol Biol. 2006 Oct;15(5):615-36. PMID: 17069637.
60. Nathanson JA. Characterization of octopamine-sensitive adenylate cyclase: Elucidation of a class of potent and selective octopamine-2 receptor agonists with toxic effects in insects. PNAS. 1985 Feb;82(3):599-603. PMID: 2982165.
61. Liu M, Plapp FW Jr. Mechanism of formamidine synergism of pyrethroids. Pestic Biochem Physiol. 1992 Aug;43(2):134-40.
62. Haarmann T, Spivak M, Weaver D, Weaver B, Glenn T. Effects of fluvalinate and coumaphos on queen honey bees (Hymenoptera: Apidae) in two commercial queen rearing operations. J Econ Entomol. 2002 Feb;95(1):28-35. PMID: 11942761.
63. Kammer AE, Heinrich B. Insect flight metabolism. Adv Insect Physiol. 1978;13:133-228.
64. Gilbert MD, Wilkinson CF. Microsomal oxidases in the honey bee, Apis mellifera. Pestic Biochem Physiol. 1973 Apr;4(1):56-66.
65. Smirle MJ, Winston ML. Detoxifying enzyme activity in worker honey bees: an adaptation for foraging in contaminated ecosystems. Can J Zool. 1988 Sep;66(9):1938-42.
66. Scott JG. Cytochrome P450 monooxygenases and insecticide resistance: lessons from CYP6D1. In: Ishaaya I, editor. Biochemical Sites of Insecticide Action and Resistance. New York (NY): Springer-Verlag; 2001. p. 255-67.
67. Casida JE, McBride L, Niedermeier RP. Insecticide metabolism, metabolism of 2,2-dichlorovinyl dimethyl phosphate in relation to residues in milk and mammalian tissues. J Agric Food Chem. 1962 Sep-Oct;10(5):370-7.
Data Sharing Statement
There are no additional data available. All raw data and code are available upon request.
Funding
This research received no funding.
Author Contributions
Whether all authors contributed significantly to the work and approve its publication.
Ethics Declaration
This article does not involve any human or animal subjects, and therefore does not require ethics approval.
Acknowledgements
We would like to express our gratitude to the patients, their families, and all those who have contributed to this study
Conflicts of Interest
No conflicts of interest in this work.
About this article
Cite this article
Padmavathi R, Sethuraj P, Rathipriya PS. Studies on Genetic Control of Insects and Public Health Importance: A Survey. Indian J Genet Mol Res. 2023;12(1):13-30.
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.