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Indian Journal of Anesthesia and Analgesia 7(2):p 493-499, Mar-Apr 2020. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.7220.8
Original Article
Single-dose Intravenous Dexmedetomidine as an Adjuvant for Prolongation of Spinal Anesthesia
Heena S Chhanwal , Divya N Kheskani , Heena S Chhanwal , Meshwa S Desai , Avni H Thacker
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Indian Journal of Anesthesia and Analgesia 7(2):p 493-499, Mar-Apr 2020. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.7220.8
How Cite This Article:
Divya N Kheskani, Heena S Chhanwal, Meshwa S Desai, et al. Single-dose Intravenous Dexmedetomidine as an Adjuvant for
Prolongation of Spinal Anesthesia. Indian J Anesth Analg. 2020;7(2):493–499.
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Received : N/A
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Abstract
Context: Dexmetedomidine is ï¡ 2 agonist used as adjuvant to spinal anesthesia for prolongation of sensory, motor block, postoperative analgesia. Aims: To study the effect of single-dose IV dexmetedomidine
on hemodynamic profile, sensory-motor block prolongation, sedation. Methods and Material: 100 adult patients of ASA 1 and 2 posted for elective infraumbilical surgery were included. They were randomly divided into 2 groups. Group D received intravenous dexmtedomidine 0.5 ïg/kg over 10 min slowly. Group M - 0.5 mg/kg over 10 mins. Both drugs were administered 15 min after spinal anaesthesia with 15 mg 0.5% intrathecal bupivacaine heavy. Vital data, duration of sensory and motor block, sensory regression, Ramsay Sedation score and side effects were evaluated. Results: Duration of sensory block
in Group D was 308 ± 20 min prolonged than Group M 200 ± 15 min. Duration of two segment regression time in Group D – 140 ± 8 min more than Group M 120 ± 6 min. Ramsay sedation score was slightly more for Group D without any respiratory depression. Patients of both groups remained hemodynamically stable through out with minimal side-effects. Conclusions: Intravenous dexmetedomidine significantly augments the sensory and motor block of intrathecal bupivacaine providing excellent sedation.
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Cite this article
Divya N Kheskani, Heena S Chhanwal, Meshwa S Desai, et al. Single-dose Intravenous Dexmedetomidine as an Adjuvant for
Prolongation of Spinal Anesthesia. Indian J Anesth Analg. 2020;7(2):493–499.
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| Received | Accepted | Published |
|---|---|---|
| N/A | N/A | N/A |
DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.7220.8
Keywords
Dexmetedomidine; Midazolam; Motor and sensory block; Sensory regressionSedation.Search for Similar Articles
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