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Indian Journal of Anesthesia and Analgesia 2(1):p 15-22, Jan-Jun 2015. | DOI: https://dx.doi.org/10.21088/ijaa.2349.8471.2115.2
Original Article
Prospective Randomized Control Study of Postoperative Epidural Analgesia of Intermittent Dosing of Bupivacaine and Clonidine vs Bupivacaine and Fentanyl
Rachana N.D. , Rachana N.D. , Saraswathi
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Indian Journal of Anesthesia and Analgesia 2(1):p 15-22, Jan-Jun 2015. | DOI: https://dx.doi.org/10.21088/ijaa.2349.8471.2115.2
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Abstract
The aim of the study was to compare the relative potencies and clinical characteristics of epidural Clonidine and Fentanyl with Bupivacaine in lower limb and lower abdominal surgeries using patient-controlled analgesia. In a randomised double-blinded study, 60 ASA I or II patients requiring epidural analgesia for post operative pain relief were allocated to receive either 0.125% Bupivacaine with Clonidine 1µg/kg or 0.125% Bupivacaine with Fentanyl 1µg/kg via a sterile syringe by trained anaesthesiologists. Analgesia was established with 10-15 ml bolus of study solution. There were significant differences in onset time, duration and quality of analgesia, local anaesthetic consumption, between the two groups. We conclude that 0.125% Bupivacaine with Clonidine 1µg/kg group of patients clinically had better quality of analgesia and for a longer duration in comparison with patients receiving 0.125% Bupivacaine with Fentanyl 1µg/kg.
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DOI: https://dx.doi.org/10.21088/ijaa.2349.8471.2115.2
Keywords
Patient-controlled analgesia; Epidural anaesthesia; Post operative pain. ÂSearch for Similar Articles
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