Abstract

Multiple Sclerosis (MS) is a chronic autoimmune condition characterized by complex motor and cognitive impairments that necessitate intensive, long-term Physiotherapy. Recent advances in Physiotherapy have shifted towards technologyintegrated approach, leveraging Virtual Reality (VR), Robot-Assisted Gait Training (RAGT), and Transcranial Direct Current Stimulation (tDCS) to enhance neuroplasticity. VR provides immersive, biofeedback-driven environments that improve postural control and patient adherence through gamification. RAGT facilitates high-intensity, repetitive gait cycles essential for improving walking endurance in severely disabled populations. Concurrently, tDCS has emerged as a potent non-invasive neuromodulatory tool to mitigate Multiple Sclerosis related fatigue and cognitive dysfunction. This review highlights how the synergy of digital innovation and evidence-based Physiotherapy is fostering a more personalized, effective, and accessible rehabilitation model, ultimately aiming to delay disability progression and improve the quality of life for individuals living with MS.

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Data Sharing Statement

Funding