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Pharmaceutical Analysis of Febuxostat: A Review

Asif Husain, Professor, Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi 110062, India. , 1Asif Husain , 2Mohd Umar Haris , 3Mustafa , 4Nawazish Sajjad , 5Santosh Soni , 6Shahzad

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Journal of Pharmaceutical and Medicinal Chemistry 7(1):p 17-21, January – June 2021. | DOI: http://dx.doi.org/10.21088/jpmc.2395.6615.7121.2

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Asif Husain, Mohd Umar Haris, Mustafa, Nawazish Sajjad, et. al., Pharmaceutical Analysis of Febuxostat: A Review. J Pharmaceut Med Chem. 2021;7(1):17-21.
 

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Abstract

Febuxostat is an orally active potent xanthine-oxidase inhibitor which inhibits the formation of uric acid thereby preventing gout. Gout is a severe chronic inflammatory disorder if not treated properly; it leads to permanent damage of body tissues and joints. Febuxostat is a well-tolerated and safe antihyperuricaemic agent that is effective to manage and treat chronic conditions of gout. Different forms are available in the market, therefore analysis of febuxostat is an important and inseparable part of industries involved in febuxostat preparations. This review covers
important properties, and different methods of analysis of Febuxostat viz. UV, HPLC, UPLC, HPTLC, LC-MS, Xray, and spectrophotometry.
Keywords: Gout; Assay; Chromatography; HPLC; Spectrophotometry; X-ray.
 

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Cite this article

Asif Husain, Mohd Umar Haris, Mustafa, Nawazish Sajjad, et. al., Pharmaceutical Analysis of Febuxostat: A Review. J Pharmaceut Med Chem. 2021;7(1):17-21.
 

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DOI: http://dx.doi.org/10.21088/jpmc.2395.6615.7121.2

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