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Review Article

Pain Perception and Incidence of Painful Procedures in Neonates: A Review of Research Evidence and Implications for Nursing Practice

Nandini Mannadath, Roshni Rani, Senthilkumar Thavasiappan

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International Journal of Pediatric Nursing 10(3):p 131-135, September - December 2024. | DOI: https://doi.org/1021088/ijpen.2454.9126.10324.6

How Cite This Article:

Nandini Mannadath, Roshni Rani, Senthilkumar Thavasiappan, Pain Perception and Incidence of Painful Procedures in Neonates: A Review of Research Evidence and Implications for Nursing Practice. Int J Pediatr Nurs. 2024;10(3):131-135.

Timeline

Received : December 02, 2024         Accepted : December 21, 2024          Published : December 30, 2024

Abstract

Pain perception in neonates and the incidence of painful procedures have been important in recent literature. This review examines the current evidence surrounding these topics: however, the implications for nursing practice remain critical. Although neonates may not articulate their pain, they experience it profoundly. Nurses must, therefore, be aware of the various factors influencing pain perception because effective management is essential. Research indicates that pain in neonates can lead to long-term consequences; this underscores the necessity for appropriate interventions. Ultimately, understanding pain perception not only enhances patient care but also informs nursing strategies, thus improving outcomes for vulnerable populations.


References

  • 1.   Anand, K. J., & Hickey, P. R. (1987). Pain and its effects in the human neonate and fetus. New England Journal of Medicine, 317(21), 1321-1329. doi:10.1056/ NEJM198711193172105
  • 2.   Anand, K. J., Hall, R. W., & Desai, N. (2019). Analgesia and anesthesia for neonates: A continuum of care. Seminars in Perinatology, 43(8), 581-590.
  • 3.   Axelin, A., Salanterä, S., Lehtonen, L., & Pelander, T. (2020). Pain assessment tools for infants: A systematic review of psychometric properties. Journal of Pediatric Nursing, 55, 68-76.
  • 4.   Badr, L. K., Summy-Long, J., & Belew, J. (2021). Impact of neonatal pain management training on nurses’ knowledge, attitudes, and practices. Pain Management Nursing, 23(4), 317-323.
  • 5.   Barker, D. P., & Rutter, N. (1995). Exposure to invasive procedures in neonatal intensive care unit admissions. Archives of Disease in Childhood. Fetal and Neonatal Edition, 72(1), F47-F48. http://www. ncbi.nlm.nih.gov/pubmed/7743285
  • 6.   Carbajal, R., Rousset, A., Danan, C., Coquery, S., Nolent, P., & Hervé, M. (2008). Epidemiology and treatment of painful procedures in neonates in intensive care units. JAMA, 300(1), 60-70. doi:10.1001/jama.300.1.60.
  • 7.   Carbajal, R., Rousset, A., Danan, C., Coquery, S., Nolent, P., Ducrocq, S., et al. (2008). Epidemiology and treatment of painful procedures in neonates in intensive care units. JAMA, 300(1), 60-70. http:// www.ncbi.nlm.nih.gov/pubmed/18594041
  • 8.   Craiq, K. D., Whitfield, M. F., Grunau, R. V., Linton, J., & Hadjistavropoulos, H. D. (1993). Pain in the preterm neonate: Behavioural and physiological indices. Pain, 52(3), 287-299. http://www.ncbi.nlm. nih.gov/pubmed/8460047
  • 9.   Fitzgerald, M., Shaw, A., & MacIntosh, N. (1988). The postnatal development of cutaneous afferent fiber input and receptive field organization in the rat spinal cord dorsal horn. Journal of Physiology, 397, 501-518. doi:10.1113/jphysiol.1988.sp017010
  • 10.   Guinsburg, R., de Araujo, P. C., Branco, M. F., Tonelotto, J., Kopelman, B. I., de Cassia, B. R., et al. (2008). Differences in pain expression between male and female newborn infants. Pain, 85(1-2), 127. http://www.ncbi.nlm.nih.gov/pubmed/10692611
  • 11.   Johnston, C. C., & Stevens, B. (2010). Developmental changes in response to pain: A review of human infant studies. Pain Research and Management, 15(4), 234-240. doi:10.1155/2010/280492
  • 12.   Johnston, C. C., Collinge, J. M., Henderson, S. J., & Anand, K. J. (1997). A cross-sectional survey of pain and pharmacological analgesia in Canadian neonatal intensive care units. Clinical Journal of Pain, 13(4), 308-312. http://www.ncbi.nlm.nih. gov/pubmed/9430811
  • 13.   Olsson, E., Mörelius, E., & Forslund, M. (2022). The effect of skin-to-skin contact on pain response in preterm and term neonates: A randomized controlled trial. Journal of Neonatal Nursing, 28(2), 107-113.
  • 14.   Pillai Riddell, R. R., Racine, N. M., & Gennis, H. G. (2021). Non-pharmacological pain management for neonates in intensive care. Pain Management Nursing, 22(3), 293-305.
  • 15.   Schiavenato, M., Byers, J. F., Scovanner, F., McMahon, J. M., Xia, Y., Lu, N., et al. Neonatal pain facial expression: Evaluating the primal face of pain. Pain, 138(2), 460-471. http://www.ncbi.nlm. nih.gov/pubmed/18692963
  • 16.   Sharley, E. A. K., Venkatesan, L., & Satchi, N. S. (2012). Effectiveness of breastfeeding upon the pain perception of infants during immunization. KNF, 7(2), 16-21.
  • 17.   Simons, S. H., van Dijk, M., Anand, K. S., Roofthooft, D., van Lingen, R. A., & Tibboel, D. (2003). Do we still hurt newborn babies? A prospective study of procedural pain and analgesia in neonates. Archives of Pediatrics & Adolescent Medicine, 157(11), 1058-1064. http://www.ncbi.nlm.nih.gov/ pubmed/14609893
  • 18.   Slater, R., Cantarella, A., Gallella, S., Worley, A., Boyd, S., Meek, J., & Fitzgerald, M. (2006). Cortical pain responses in human infants. Journal of Neuroscience, 26(14), 3662-3666. doi:10.1523/ JNEUROSCI.0348-06.2006

Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

No conflicts of interest in this work.


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Cite this article

Nandini Mannadath, Roshni Rani, Senthilkumar Thavasiappan, Pain Perception and Incidence of Painful Procedures in Neonates: A Review of Research Evidence and Implications for Nursing Practice. Int J Pediatr Nurs. 2024;10(3):131-135.


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


Received Accepted Published
December 02, 2024 December 21, 2024 December 30, 2024

DOI: https://doi.org/1021088/ijpen.2454.9126.10324.6

Keywords

Pain perceptionIncidence of pain in neonatesNeonatal painPainful procedures in neonatesNursing practice

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Timeline


Received December 02, 2024
Accepted December 21, 2024
Published December 30, 2024

licence


Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


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