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Case Report

Orbital Rhabdomyosarcoma Masquerading as a Sinonasal Carcinoma: Case Report

Virendra Bhandari, null, Neha Singh Rajput1 null, Dipshi Agrawal2 null, Ashar Iqbal Lodi3 null, Virendra Bhandari4 null

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Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.

Indian Journal of Cancer Education and Research 12(2):p 92-95, July- Dec. 2024. | DOI: https://doi.org/10.21088/ijcer.2321.9815.12224.8

How Cite This Article:

Neha Singh Rajput, Dipshi Agrawal, Ashar Iqbal Lodi, Virendra Bhandari, Orbital Rhabdomyosarcoma Masquerading as a Sinonasal Carcinoma: Case Report. Ind J Canc Educ Res 2024;12(2):92-95.
 

Timeline

Received : July 02, 2024         Accepted : January 15, 2024          Published : July 31, 2024

Abstract

Background: Rhabdomyosarcoma (RMS), the most common soft tissue sarcoma in children. While most children with localized RMS achieve long-term remission, the prognosis for those with metastatic RMS continues to be challenging, with limited improvements in survival outcomes. Aim: This report aims to highlight a rare case of orbital rhabdomyosarcoma (RMS) initially misdiagnosed as a sinonasal carcinoma. Objectives: Initially suspected to be sinonasal carcinoma, histopathological analysis revealed a malignant round cell tumor. Immunohistochemistry (IHC) further confirmed the diagnosis as embryonal rhabdomyosarcoma. This report studies the role of radiation in orbital Rhabdomyosarcoma. Material: At the SAIMS institute’s Radiation Oncology Department, pathology records were examined for case of Rhabdomyosarcoma. The treatment approach for this patient included a combination of radiation therapy and chemotherapy. Result: We found that throughout the course of radiation therapy patient shows excellent tolerance and patient is on regular follow up in our department. Conclusion: Orbital RMS has a relatively optimistic prognosis due to its favorable location and histology. In cases where surgery isn’t possible, radiotherapy remains essential, offering strong response rates with manageable side effects.
 

References

  • 1.   Singh, Aditya Pratap; Gupta, Arun Kumar; Mathur, Vinay; Barolia, Dinesh Kumar. Embryonal
  • 2.   Karakosta C, Liaskou M, Kattamis A, Rigatou E, Paraskevopoulos K. Orbital Rhabdomyosarcoma Masquerading as a Dermoid Cyst: A Case Report and Review of the Literature. Cureus. 2023 Dec 11;15(12).
  • 3.   Puri DR, Wexler LH, Meyers PA, La Quaglia MP, Healey JH, Wolden SL. The challenging role of radiation therapy for very young children with rhabdomyosarcoma. International Journal of Radiation Oncology* Biology* Physics. 2006 Jul
  • 4.   Cameron AL, Elze MC, Casanova M, Geoerger B, Gaze MN, Minard-Colin V,et al. The impact of radiation therapy in children and adolescents with metastatic rhabdomyosarcoma. International Journal of Radiation Oncology* Biology* Physics. 2021 Nov 15;111(4):968-78.
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Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

No conflicts of interest in this work.

About this article

Cite this article

Neha Singh Rajput, Dipshi Agrawal, Ashar Iqbal Lodi, Virendra Bhandari, Orbital Rhabdomyosarcoma Masquerading as a Sinonasal Carcinoma: Case Report. Ind J Canc Educ Res 2024;12(2):92-95.
 

Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.

Received Accepted Published
July 02, 2024 January 15, 2024 July 31, 2024
DOI: https://doi.org/10.21088/ijcer.2321.9815.12224.8

Keywords

Orbital tumorsEmbryonal rhabdomyosarcomaSinonasal carcinoma.Embryonal rhabdomyosarcomaSinonasal carcinoma.

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Timeline

Received July 02, 2024
Accepted January 15, 2024
Published July 31, 2024

licence

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


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