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Journal of Pharmaceutical and Medicinal Chemistry 8(1):p 37-38, January-June 2022. | DOI: https://doi.org/10.21088/jpmc.2395.6615.8122.4
Case Report
Management of Troublesome Intrathecal Fentanyl Induced Pruritis
Dheeraj Kumar, S P Sharma, Sunny Eapen
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Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
Journal of Pharmaceutical and Medicinal Chemistry 8(1):p 37-38, January-June 2022. | DOI: https://doi.org/10.21088/jpmc.2395.6615.8122.4
How Cite This Article:
S P Sharma, Sunny Eapen, Dheeraj Kumar/Management of Troublesome Intrathecal Fentanyl Induced Pruritis/J Pharmaceut Med Chem. 2022;8(1):37-38Timeline
Received : April 14, 2022
Accepted : May 11, 2022
Published : June 25, 2022
Abstract
Combination of intra thecal local analgesic and opioid are commonly used for neuraxial blocks. This combination gives excellent intraoperative as well as postoperative analgesia. Pruritus is a troublesome side effect of intrathecal opioids. Sometimes it may be more unpleasant than pain itself. We experienced a case of severe pruritis evoked by intrathecal fentanyl in a patient with Intertrochanteric fracture (Rt) femur for ORIF. After 90 minutes of intrathecal administration of a combination of bupivacaine and fentanyl she began to complain of severe itching which was managed with Inj Hydrocortisone Succinate. After surgery patient was shifted to ward for close monitoring. General isedprurit is and tachypnoea recurred after 18 hours which responded only to naloxone infusion for 6 hrs. Therefore it is suggested that naloxone is useful to reverse the effect of fentanyl inducedpruritis.
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Data Sharing Statement
There are no additional data available. All raw data and code are available upon request.
Funding
This research received no funding.
Author Contributions
All authors contributed significantly to the work and approve its publication.
Ethics Declaration
This article does not involve any human or animal subjects, and therefore does not require ethics approval.
Acknowledgements
We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.
Conflicts of Interest
No conflicts of interest in this work.
About this article
Cite this article
S P Sharma, Sunny Eapen, Dheeraj Kumar/Management of Troublesome Intrathecal Fentanyl Induced Pruritis/J Pharmaceut Med Chem. 2022;8(1):37-38
Licence:
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
| Received | Accepted | Published |
|---|---|---|
| April 14, 2022 | May 11, 2022 | June 25, 2022 |
DOI: https://doi.org/10.21088/jpmc.2395.6615.8122.4
Keywords
FentanylNaloxonePruritisSearch for Similar Articles
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Timeline
| Received | April 14, 2022 |
| Accepted | May 11, 2022 |
| Published | June 25, 2022 |
licence
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
