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Case Report

Kikuchi Fujimoto Disease: A Rare Case Report

Rajeev N. , Rajeev N. , Anuroop Thota

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New Indian Journal of Surgery 4(2):p 47-51, July - December 2013. | DOI:

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Abstract

Introduction: Kikuchi-Fujimoto disease (histiocytic necrotizing lymphadenitis) is a rare, benign, self limiting syndrome characterized by tender regional lymphadenopathy, fever and night sweats. Highest prevalence is seen among Japaneese population. Case Report: We report a case of a young male presenting with fever with chills and tender cervical lympadenopathy not responding to the traditional treatment. A fine needle aspiration cytology of the lymph node was done, which was inconclusive. An excision biopsy showed features suggestive of Kikuchi Fujimoto’s disease. Patient was started on low dose steroids with anti inflammatory drugs. Patient became symptom free within a week and has no recurrence in 6 months of follow up. Discussion: Kikuchi disease is mainly a diagnosis of exclusion. It is self-limited, and lasts 1 to 4 months with a low, but possible, recurrence rate of 3% to 4%. Only 3 fatal cases have been reported, occurring in the active phase of probably genuine disease. It has no specific treatment. Only symptomatic treatment measures to relieve local and systemic complaints should be used. Patients with a more severe clinical course or with relapsing signs and symptoms could benefit temporarily from corticosteroids. Conclusion: Kikuchi Fujimnoto disease is rare and a self limited disease, diagnosis of which is based on histopathological findings. It should be suspected in all the cases of unexplained fever and tender lymphadenopathy thus avoiding cumbersome investigations. It usually responds to symptomatic treatment and in unresponsive patients, low dose steroids for 10 days helps to prevent relapse and recurrence, as in our case. 

Keywords: Kikuchi Fujimoto disease; Histiocytic necrotising lymphadenitis; Pyrexia; Lymphadenopathy; Corticosteroids.  

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