Home > Journals > Indian Journal of Anesthesia and Analgesia

Indian Journal of Anesthesia and Analgesia

Submit your article Read this Journals View all journals
Full Text (PDF)
Original Article

Ketamine 0.5 mg.kg-1 as Co-induction Agent with Propofol 2.5 mg.kg-1 Vs Propofol 3.5 mg.kg-1 for Laryngeal Mask Airway Insertion in Children: A Clinical Comparative Study

Ashwini S , Kumara AB1 , Ashwini S2 , Gurudatta KN3

Author Information

Licence:



Indian Journal of Anesthesia and Analgesia 6(6):p 2133-2137, November-December 2019. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.6619.40

How Cite This Article:

Kumara AB, Ashwini S, Gurudatta KN. Ketamine 0.5 mg.kg-1 as Co-induction Agent with Propofol 2.5 mg.kg-1 Vs Propofol 3.5 mg.kg-1 for Laryngeal Mask Airway Insertion in Children: A Clinical Comparative Study. Indian J Anesth Analg. 2019;6(6 Part - II):2133-2137.

Timeline

Received : N/A         Accepted : N/A          Published : N/A

Abstract

Introduction: Propofol is the widely used induction agent for smooth insertion of laryngeal mask in children who require a larger dose compared to adults1–3 and hemodynamic and respiratory effects like hypotension,2,4 bradycardia, apnoea, hypoventilation4 may be exaggerated. The present study was undertaken with the objectives to assess (i) effectiveness of ketamine as a co-induction agent in lowering the induction dose of propofol while producing favorable insertion characteristics for Laryngeal Mask Airway insertion in children (ii) safety in producing hemodynamic stability (iii) recovery of the patient. Methods: ASA I and II, aged 3–10 years children posted for elective short surgical procedures were allocated randomly into two groups of 30 each. Patients in Group P received propofol 3.5 mg.kg-1 and Group KP received intravenous ketamine 0.5 mg. kg-1 two minutes prior to propofol 2.5 mg.kg-1. LMA insertion characteristics assessed in the next 30s using (1) “mouth opening” graded on a three-point scale-full, partial and impossible (2) “the ease of LMA insertion” graded on a four-point scale-easy, some difficulty, difficult and impossible. The hemodynamic parameters recorded immediately after ketamine, propofol (0 min), thereafter at 1 minute interval for 5 minutes. At the end of surgery, LMA removed once the child was adequately recovered. Statistical evaluation done using Frequencies and Crosstabs, Paired Sample t - test and Repeated measure ANOVA. Results: Ketamine as a co-induction agent with propofol produced favorable conditions for smooth insertion of laryngeal mask in children while providing greater hemodynamic stability.

References

No records found.


About this article

Cite this article

Kumara AB, Ashwini S, Gurudatta KN. Ketamine 0.5 mg.kg-1 as Co-induction Agent with Propofol 2.5 mg.kg-1 Vs Propofol 3.5 mg.kg-1 for Laryngeal Mask Airway Insertion in Children: A Clinical Comparative Study. Indian J Anesth Analg. 2019;6(6 Part - II):2133-2137.

Licence:



Received Accepted Published
N/A N/A N/A
DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.6619.40

Keywords

Co-induction; Ketamine; Propofol; Laryngeal mask airway.

Article Level Metrics

Last Updated

Monday 13 July 2026, 05:10:32 (IST)

5647

Accesses

5
678
00

Citations


NA
NA
NA

Download citation


Article Keywords

Keyword Highlighting

Highlight selected keywords in the article text.


Timeline

Received N/A
Accepted N/A
Published N/A

licence




Access this article

Reprint Order Form
Buy this Article
Institutional Subscriptions

Share