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Intracranial Haemorrhage in Childhood ITP: An Unfortunate Twist of Fate

Chaitanya Pendyala, Department of Pediatrics, 1st Floor, College Building, TN Medical College and BYL Nair Charitable Hospital, Dr. AL Nair Road, Mumbai Central, Mumbai400008. , Chaitanya Pendyala* , Alpana Kondekar** , Purvi Kadakia*** , Radha Ghildiyal**** , Richa*

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Pediatric Education and Research 5(2):p 101-103, May-Aug 2017. | DOI: https://dx.doi.org/10.21088/per.2321.1644.5217.19

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Abstract

Immune thrombocytopenic purpura (ITP) is a clinical syndrome in which a decreased number of circulating platelets (thrombocytopenia) manifests as a bleeding tendency, easy bruising (purpura), or extravasation of blood from capillaries into skin and mucous membranes (petechiae). Although most cases of acute ITP, particularly in children, are mild and selflimited, intracranial hemorrhage may occur when the platelet count drops below 10 × 109/L (<10 × 103/µL); this occurs in 0.51% of children, and half of these cases are fatal. Intracranial haemorrhage is a rare but life threatening complication of childhood Immune Thrombocytopenic Purpura. Aggressive multi – modality treatment is warranted in such cases.

Keyword: Immune thrombocytopenic purpura (ITP); Intracranial Haemorrhage. 


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DOI: https://dx.doi.org/10.21088/per.2321.1644.5217.19

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