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Incidence and Predictors of Contrast Induced Nephropathy after Percutaneous Coronary Intervention at a Tertiary Care Hospital in Western India

Rahul Jain , Cinosh Mathew , Rahul Jain , Nishant Saxena , Jayesh Rawal

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Journal of Cardiovascular Medicine and Surgery 6(2):p 127-131, April – June 2020. | DOI: http://dx.doi.org/10.21088/jcms.2454.7123.6220.6

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Cinosh Mathew, Rahul Jain, Nishant Saxena, et al. Incidence and Predictors of Contrast Induced Nephropathy after Percutaneous Coronary Intervention at a Tertiary Care Hospital in Western India. J Cardiovasc Med Surg 2020;6(2):127-131.
 

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Abstract

Aims: This observational study was undertaken to identify the incidence of contrast induced nephropathy and the predictors for development of Contrast induced Nephropathy after Coronary Angioplasty in a tertiary
care institute.

Materials and Methods: The study consisted of 520 patients who underwent Percutaneous Coronary Angioplasty at our institute during one year duration and who satisfied the inclusion criteria were enrolled in the study. Renal parameters such as serum Creatinine and Blood Urea level was measured at baseline and at 24 hours and 48 hours post procedure. Contrast induced nephropathy was defined as an increase of >25% or >0.5 mg/dl in pre-catheterization serum creatinine at or after 48h after percutaneous coronary intervention. Standard definitions were used to define the variables.

Results: 67 patients (12.88%) developed Contrast induced Nephropathy post PCI in the study. Elderly population, presence of diabetes mellitus, hypertension, anemia were associated with the risk of developing CIN and found to be statistically significant. Increased Contrast volume and raised baseline creatinine also were also found to be associated with CIN.

Conclusions: Development of CIN is a known complication of PCI and can be mostly prevented if patients with risk factors are identified and preventive measures taken based on guideline based recommendations.

 

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Cinosh Mathew, Rahul Jain, Nishant Saxena, et al. Incidence and Predictors of Contrast Induced Nephropathy after Percutaneous Coronary Intervention at a Tertiary Care Hospital in Western India. J Cardiovasc Med Surg 2020;6(2):127-131.
 

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DOI: http://dx.doi.org/10.21088/jcms.2454.7123.6220.6

Keywords

Contrast induced nephropathy; Percutaneous coronary intervention; Contrast media.

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