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Indian Journal of Anesthesia and Analgesia

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How Efficacious Intrathecal Dexmedetomidine with Levobupivacaine in Lower Limb Surgeries: A Comparative Study

Richa Chandra, Assistatn Professor, Dept of Anaesthesiology and Critical Care, Sri Ram Murti Smarak Institute of Medical Sciences, Bareilly, Uttar Pradesh 243001, India. , Mahesh Kashyap1 , Richa Chandra2

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Indian Journal of Anesthesia and Analgesia 5(4):p 566-573, April 2018. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.5418.10

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Abstract

Background and Aim: Studies and research are ongoing to find appropriate adjuvants to intrathecal local anaesthetic agents to make them more effective and economical. In view of the same we undertook a study with Levobupivacaine, being a newer agent with more cardiac stability and compared the outcomes with 3 adjuvants (REF).

Settings and Design: After approval from hospital ethical committee a randomized double blind study was conducted among 60 healthy American Society of Anesthesiologist ASA I and II patients, scheduled for lower limb surgeries. The study was conducted over 1 year at SRMSIMS.

Materials and Methods: Spinal block was administered in L3 and L4 intervertebral space, using 0.5% Levobupivacaine 12mg. Adjuvants were added in group 1, Dexmedetomidine 5mcg, and in group 2, Dexmedetomidine 10 mcg. Anaesthetic level achieved was T10. Onset time to achieve sensory, motor blockade, their regression time was noted. Hemodynamic changes and requirement for other analgesic drug was also noted.

Results: 60 patients were enrolled in our study; the data was recorded and analyzed using statistical analysis.

Conclusion: To conclude, Levobupivacaine with Dexmedetomidine, gives better result for intra as well as for postoperative regional anaesthesia without any adverse effects.

 

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DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.5418.10

Keywords

Adjuvants; Intrathecal; Levobupivacaine; Dexmedetomidine Clonidine.

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