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Gamma-Glutary Transferase: A Novel Biomarker for Predicting Coronary Artery Disease

Arun BS , Sandeep J Bijapur , Arun BS , Manjunath C Nanjappa , Tejeswar Reddy P , Rockey Katheria ,

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Journal of Cardiovascular Medicine and Surgery 6(1):p 29-32, January-March 2020. | DOI: http://dx.doi.org/10.21088/jcms.2454.7123.6120.5

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Sandeep J Bijapur, Arun BS, Manjunath C Nanjappa et al. Gamma-Glutary Transferase: A Novel Biomarker For Predicting Coronary Artery Disease. J Cardiovasc Med Surg. 2020;6(1):29-32.


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Abstract

Background: Gamma Glutamy l Transferase (GGT) is involved in pathogenesis of various cardiovascular diseases. Aim: To assess serum GGT level in predicting significant CAD (Coronary Artery Disease).

Methods: 200 patients undergoing CAG were studied. Serum GGT level was compared between normal/insignificant CAD Group (Group 1) and significant CAD Group (Group 2). Comparison between various subgroups was done.

Results: Mean age of study population was 57.63 ± 10.78 years. Mean of serum GGT level in Group 1 was 31.61 ± 20.17 and in Group 2 was 39.48 ± 22.91. (p = 0.004). Mean ± SD of SVD, DVD and TVD were 43.29 ± 24.05, 36.8 ± 20.47 and 39.06 ± 26.04 and were not statistically significant.

Conclusion: Serum GGT level can be used as a noninvasive biomarker to predict significant CAD.

 


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Sandeep J Bijapur, Arun BS, Manjunath C Nanjappa et al. Gamma-Glutary Transferase: A Novel Biomarker For Predicting Coronary Artery Disease. J Cardiovasc Med Surg. 2020;6(1):29-32.


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DOI: http://dx.doi.org/10.21088/jcms.2454.7123.6120.5

Keywords

Gamma-glutamyltransferase; Biomarker; Coronary artery disease.

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