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Letter to Editor

Fat, Hyperlipidemia and Hypercholesterolemia in Diabetic Peripheral Neuropathy

Kumar Senthil P. , Kumar Senthil P. , Adhikari Prabha , Jeganathan

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International Journal of Food, Nutrition & Dietetics 1(2):p 69-70, May-Aug 2013. | DOI:

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Abstract

This letter to editor was aimed at expanding the interprofessional understanding on the role of nutritioninduced hematological adaptations such as hyperlipidemia and hypercholesterolemia secondary to fat intake in diet and nutrition in diabetic peripheral neuropathy (DPN).Hypercholesterolemia induced genetic variation in tumor necrosis factor (TNF) receptor 2 gene, High-fat diet fed streptozotocin-induced diabetic rats not only developed peripheral neuropathy faster than their controls[ 2,3] but also associated disorders like cholesterolinduced gall bladder stones[ 4] and many intervention studies had shown efficacy for controlling hyperlipidemia and co-existing mechanical ad thermal allodynia in experimental models of DPN. Hyperlipidemia is thus to be regarded as a new therapeutic target for DPN. 

 

Keywords: Food; Nutrition; Diet; Hyperlipidemia; Hypercholesterolemia; Diabetic neuropathy. 

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