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Estimation Early Neonatal Hyperbilirubinemia Utilizing 24-hour Serum Bilirubin Level at Bhuj, Kutch

Arun Parikh, Associate Professor, Dept. of Paediatrics, Gujarat Adani Institute of Medical Science, Bhuj, Kutch, Gujarat 370001, India. , Arun Parikh1 , Abhikumar Shingala2

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Pediatric Education and Research 6(2):p 84-89, May - August 2018. | DOI: DOI: https://dx.doi.org/10.21088/per.2321.1644.6218.7

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Abstract

Background and Aim: Jaundice is the frequent irregular physical finding in the first week of life Jaundice is the noticeable form of hyperbilirubinemia. The present study was performed with an aim to evaluate the predictive value of TSB=6 mg/dl at 24±6 hours of age in identifying infants.

Material and Methods: The present forthcoming study was performed at Department of Pediatrics, at a tertiary care hospital, Bhuj. All fit neonates were to be examining for TSB levels at 24 hours and over again at 5 days. Serum bilirubin was expected for all registered cases within 18 to 30 hour of life spectrophotometrically utilizing twin Beam method. Children after that followed up clinically for the manifestation and development of jaundice every 12 hour till discharge from the department. TSB estimation was repeated if the clinical assessment of jaundice was more than 10 mg/dl by any observer using Kramers Rule.

Results: A total of 199 neonates were originally enrolled. 37 of 199 cases did not follow up. Significant Hyperbilirubinemia was present in 20.9% cases of those babies who developed jaundice. A TSB of <6mg/dl at 24+6 hours was there in 99 infants. In the due 49 cases the TSB at 24+6 hours was >6 mg/dl. 20 cases out of this eventually went on to develop a positive study outcome. Sensitivity of TSB at 24+6 hours >6mg/dl in recognizing those who will have hyperbilirubinemia =90.9%, Specificity was 76.12%, Positive predictive value was 41.6% and Negative predictive value was 97.9%.

Conclusion: The current research establishes that a TSB at 24+6 hours <6mg/dl has a elevated predictive value in recognizing those infants who are doubtful to build up consequent hyperbilirubinemia and these neonates can be released before time from the hospital.

Keywords: Infants; Hyperbilirubinemia; Jaundice; Sensitivity; Specificity.

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DOI: DOI: https://dx.doi.org/10.21088/per.2321.1644.6218.7

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