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Indian Journal of Anesthesia and Analgesia

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Effects of Intrathecal 5µg Dexmedetomidine with Hyperbaric Bupivacaine as Compared to Plain Bupivacaine on Hemodynamic Changes

Naveed Ahmed, Assistant Professor, Dept. of Anaesthesia, Dr. BR Ambedkar Medical College, Bangalore, Karnataka 560045, India. , Naveed Ahmed1 , Shabbir Ali Jaferali Mulla2

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Indian Journal of Anesthesia and Analgesia 4(4):p 1013-1018, October-December 2017. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.4417.16

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Abstract

Introduction: Spinal anesthesia is characteristically associated with slowing of the rate. The degree of bradycardia as well as the frequency with which it can he roughly correlated with the extent of sympathetic denervation. Pronounced bradycardia is observed most frequently when cardiac output and arterial blood pressures have decreased significantly during anesthesia. Methodology: 60 patients selected for this study were randomly divided into two groups; each group comprised of 30 patients each. Written informed consent was taken from all patients who participated in the study. Preoperative assessment with complete history, general physical examination and systemic examination was done for each patient along with airway assessment and spinal column examination. Results: The changes in heart rate at different intervals of time was not found to be statisticallysignificant between two groups. In group DB, the mean difference of heart rate from basal to 90 minutes, was 10.47 minutes and whereas among PB group, it was 3.83 minutes. This implies that heart rate reduction is more in case of DB group compared to PB group but it was not statistically significant Conclusion: There was a difference in basal MAP between two groups which was not statically significant.

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DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.4417.16

Keywords

Dexmedetomidine; Hyperbaric Bupivacaine; Hemodynamic Changes. 

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