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Effect of Propofol and Fentanyl with the Controls to Prevent Emergence Agitation in Children Receiving Sevoflurane for Adenotonsillectomy

Dr. G.M. Jagadeesh, Resident, Institute of Anaesthesiology, Madurai Medical College, Madurai – 625020, Tamil Nadu, India. , D.S. Sudhakar1 , G.M. Jagadeesh2 , Shanmugam3

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Indian Journal of Anesthesia and Analgesia 4(3):p 639-645, July - September 2017. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.4317.15

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Abstract

Background: The administration of a single dose of propofol is reported to be effective in decreasing the incidence and severity of emergence agitation in children following sevoflurane anesthesia. Aim: Tocompare the effect of propofol and fentanyl with the control group to prevent emergence agitation in children receiving sevoflurance for adenotonsillectomy. Materials and Methods: Sixty childrens of ASAI of either sex divided into three groups. Twenty children in each group. Group FF: Children given 1.5 mcg/kg fentanyl during induction, and 1.0 mcg/kg fentanyl at the end of surgery, Group FP: Children given 1.5 mcg/kg fentanyl during induction, and 1 mg/kg propofol, Group FN: Children given 1.5 mcg/kg fentanyl during induction, and 0.1 ml/kg normal saline at the end of surgery. Results: In our study group the age of the children, sex distribution, weight, are not statically significant. Intra operative monitoring of pulse rate, spo2 and duration of sevoflurance administration, duration of surgery are also not statistically significant. Aono’s four point scale which is used to determine the presence of emergence agitation showed statistically significant reduction in group FPand group FF compare with the group FN. The PAED score used to find out the severity of the emergence agitation and the CHIPPS score are statistically not significant. The P value of Ramsay sedation score in the group FN and Group FF is 0.016. and it’s statistically significant and the P value between group FN and group FP is 0.035. it’s also statistically significant. Conclusion: Propofol and fentanyl has been useful in reducing the incidence of emergence agitation for adenotonsillectomy surgeries in children receiving sevoflurane.

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DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.4317.15

Keywords

Adenotonsillectomy; Propofol; Fentanyl. 

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