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Effect of Platelet Rich Plasma in Knee Osteoarthritis

Satyendra Tripathi , Apurva Agarwal1 , Satyendra Tripathi2 , Manoj Chaurasia3 , Saurabh Agarwal4 , Ashok Kumar Verma5

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Indian Journal of Anesthesia and Analgesia 7(4):p 969-976, July-Aug 2020. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.7420.18

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Apurva Agarwal, Satyendra Tripathi, Manoj Chaurasia et al. Effect of Platelet Rich Plasma in Knee Osteoarthritis. Indian J Anesth Analg. 2020;7(4):969–976.
 

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Received : N/A         Accepted : N/A          Published : N/A

Abstract

Back ground and Aims: This study aims to evaluate the effectiveness of intra-articular injection of platelet rich plasma (PRP)in reducing pain and improving physical function, in osteoarthritis. Method: Prospective longitudinal study comprising of 100 patient& divided into 3groups according to Kallgren & Lawrence grading of osteoarthritis of knee and followed up for period of 1 year (january18 to October 19). All patients were treated with intraarticular PRP injection (C-arm guided) in affected knee at 4weeks apart. VAS (Visual analog scale), KOOS (knee injury osteoarthritis outcome score) used for clinical evaluation. Data analyzed using SPSS software 22.0. Result: Outcome were almost similar for grade 1&2 though intensity of pain showed significant improvement
even in grade3(p<0.05). on the basis of VAS SCORE Highly significant improvement in pain in Grade1 and Grade2 osteoarthritis having p value<0.0001 and significant improvement in Grade3 osteoarthritis having p value=0.003(<0.05). On the basis of KOOS SCORE all the parameter like pain symptom, functional daily activity, sport & recreational activity and quality of life highly significant improve in Grade1&2 pvalue<0.0001 and for Grade3 significant improvement in all parameter having p value<0.05. Conclusion: PRP injection is a cost effective, reliable, minimal invasive, no side effect, good efficacy & used
in less equipped setting. And showed clinical as well as functional improvement in VAS score and KOOS score. It is highly significant for grade 1 and 2 and significant for grade 3 osteoarthritis.

 

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Cite this article

Apurva Agarwal, Satyendra Tripathi, Manoj Chaurasia et al. Effect of Platelet Rich Plasma in Knee Osteoarthritis. Indian J Anesth Analg. 2020;7(4):969–976.
 

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DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.7420.18

Keywords

Platelet rich plasma (PRP); Knee injury & osteoarthritis outcome score (KOOS); Visual analogue scale.

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