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New Indian Journal of Surgery 16(1):p 7-11, Jan -March 2025. | DOI: 10.21088/ijamy.0974.6986.16125.1
Original Article
Effect of Early Surgery on Pain in Patients with Chronic Pancreatitis
Aravind K., Chandana M.S, Senthan Srirangaswamy, Mahesh Tiwari
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Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
New Indian Journal of Surgery 16(1):p 7-11, Jan -March 2025. | DOI: 10.21088/ijamy.0974.6986.16125.1
How Cite This Article:
Chandana MS, Aravind K, et al. Effect of Early Surgery on Pain in Patients with Chronic Pancreatitis. New Indian J Surg. 2025;16(1):7-11.Timeline
Received : February 20, 2025
Accepted : March 21, 2025
Published : March 25, 2025
Abstract
Introduction: Chronic pancreatitis (CP) is a progressive fibro-inflammatory disease of the pancreas with an increasing annual incidence characterized by intractable pain and poor quality of life. The timing of surgery for painful chronic pancreatitis (CP) may affect outcomes. Methods: After IEC Clearance Consecutive CP patients diagnosed by disease history and radiological findings who underwent surgery at KIMS Hospital between March 2021 and May 2023. They were followed up for 18 months. The primary endpoint was pain relief, assessed at the end of follow-up using the Izbicki pain score. Results: 40 patients of pancreatitis who underwent surgery were studied retrospectively for the association of disease duration with outcome of pain relief. The patients were divided into early (< 3 years) and late groups (>3 years) based on the duration of abdominal pain.In these 80% of them had pain of <3 years duration, and the remaining 20% had pain of >3 years duration. Among these 77.5% were alcoholic and 12.5% had diabetes. On CECT evaluation, 35% had dilated pancreatic duct (> 10 mm) and the remaining 65% had duct size of <10 mm. Among these 82.5% underwent Frey’s procedure, LPJ was done in the remaining (17.5%). After surgery 90% had relief of postoperative pain and majority (62.5%) had long duration of stay (>2 weeks). There was a significant difference in Gender, Procedure done, Diabetes mellitus, Alcoholism, CECT duct size, and post-operative pain between early and late groups. There was no significant difference in Age, Steatorrhea, and duration of stay between early and late groups. Conclusion: Earlier surgery improves outcomes from painful chronic pancreatitis.
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This research received no funding.
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All authors contributed significantly to the work and approve its publication.
Ethics Declaration
This article does not involve any human or animal subjects, and therefore does not require ethics approval.
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Cite this article
Chandana MS, Aravind K, et al. Effect of Early Surgery on Pain in Patients with Chronic Pancreatitis. New Indian J Surg. 2025;16(1):7-11.
Licence:
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
| Received | Accepted | Published |
|---|---|---|
| February 20, 2025 | March 21, 2025 | March 25, 2025 |
DOI: 10.21088/ijamy.0974.6986.16125.1
Keywords
CP - Chronoc pancreatitisLPJ - Longitudinal pancreaticojejunostomytis • LPJ - Longitudinal pancreaticojejunostomy • CECT - Con• LPJ - Longitudinal pancreaticojejunostomy • CECT -Contrast enhanced CT- Contrast enhanced CTCECT-Contrast enhanced CTSearch for Similar Articles
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Timeline
| Received | February 20, 2025 |
| Accepted | March 21, 2025 |
| Published | March 25, 2025 |
licence
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
