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Indian Journal of Trauma and Emergency Pediatrics 15(2):p 47-52, April - June 2023. | DOI: https://doi.org/10.21088/ijtep.2348.9987.15223.2
Case Report
Duplication Cysts and Autoimmune Hemolytic Anemia: An Association or a Coincidence?
Milind S. Tullu, Sidaraddi Sanju, Rucha Tonge, Mukesh Agrawal
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Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
Indian Journal of Trauma and Emergency Pediatrics 15(2):p 47-52, April - June 2023. | DOI: https://doi.org/10.21088/ijtep.2348.9987.15223.2
How Cite This Article:
Sidaraddi Sanju, Milind S. Tullu, Rucha Tonge, et al./Duplication Cysts and Autoimmune Hemolytic Anemia: An Association or a Coincidence?/Indian J Trauma Emerg Pediatr.2023;15(2):47–52.Timeline
Received : April 03, 2023
Accepted : April 27, 2023
Published : June 30, 2023
Abstract
Duplication cysts are rare congenital anomalies of the gastrointestinal tract and the occurrence of multiple such cysts is an extremely rare occurrence. Autoimmune hemolytic anemia is an extremely unusual manifestation of these duplication cysts. Herein, we report a case with two duplication cysts (one cyst in the thorax; another in the abdomen) complicated with autoimmune hemolytic anemia. This patient was a five year-old-male child who presented with congestive cardiac failure due to severe anemia (which, on evaluation, was diagnosed as autoimmune hemolytic anemia). Imaging studies (chest radiograph and computed tomography) revealed duplication cysts in the chest and abdomen. Anemia flare-up was noted in the patient despite two months of prednisolone therapy (2 mg/kg/day) and two high dose intravenous methylprednisolone pulse therapy courses (30 mg/kg/day for 5 days each). The steroid refractory autoimmune hemolytic anemia responded to rituximab (375 mg/m2 body surface area/week for 4 weeks). Four months after tapering off the steroid therapy, the patient did not experience flare-up of the anemia. To the best of our knowledge, this is the youngest and first pediatric age group patient to be reported, with a possible association between gastrointestinal duplication cysts with autoimmune hemolytic anemia.
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There are no additional data available. All raw data and code are available upon request.
Funding
This research received no funding.
Author Contributions
All authors contributed significantly to the work and approve its publication.
Ethics Declaration
This article does not involve any human or animal subjects, and therefore does not require ethics approval.
Acknowledgements
We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.
Conflicts of Interest
No conflicts of interest in this work.
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Cite this article
Sidaraddi Sanju, Milind S. Tullu, Rucha Tonge, et al./Duplication Cysts and Autoimmune Hemolytic Anemia: An Association or a Coincidence?/Indian J Trauma Emerg Pediatr.2023;15(2):47–52.
Licence:
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
| Received | Accepted | Published |
|---|---|---|
| April 03, 2023 | April 27, 2023 | June 30, 2023 |
DOI: https://doi.org/10.21088/ijtep.2348.9987.15223.2
Keywords
Autoimmune hemolytic anemiaBlood transfusionChildComputed tomography (CT)Duplication cystParaneoplastic syndromeRituximabSearch for Similar Articles
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Timeline
| Received | April 03, 2023 |
| Accepted | April 27, 2023 |
| Published | June 30, 2023 |
licence
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
