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Studies on Genetic Environment Influences on the Development of Childhood Psychiatric Disorders: A Review

P. Sethuraj, R. Padamavati, P.S. Rathipriya

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Indian Journal of Trauma and Emergency Pediatrics 15(2):p 41-44, April - June 2023. | DOI: https://doi.org/10.21088/ijtep.2348.9987.15223.1

How Cite This Article:

R. Padamavati, P. Sethuraj, P. S. Rathipriya/Studies on Genetic Environment Influences on the Development of Childhood Psychiatric Disorders; A Review/Indian J Trauma Emerg Pediatr.2023;15(2):41–44.

Timeline

Received : April 17, 2023         Accepted : May 02, 2023          Published : June 30, 2023

Abstract

This research article review the key types of genetic research design, methodology involved and emerging and established finding in relation to child and childhood psychiatric disorders, and finally genetic factors seems especially important for autism and attention deficit hyperactivity disorder. (Thapar and McGuffin, 2008)1 Twin and adoption study design are now being used to examine gene environment interplay, the effects of environment risk factors co-morbidity phenotype definition and development change Liu et al (2006)11 The ways in which specific gene variant excert risk effects at cellular and biological system are proving to highly competitive (Moffitt et al, 2005).2 Finally, molecular genetic studies also high light the importance of gene environment interply, which seems to be especially important in depression and wide anti social behavior. Liu. et al)11, owen et al 2005)12 , Moffitt, et al, (2005)2


References

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  • 2.   Moffitt TE, Caspi A, Rutter M. Strategy for investigating interactions between measured genes and measured environments. Arch Gen Psychiatry. 2005;62(5):473–81.
  • 3.   Thapar A, Harold G, Rice F, Langley K, O'Donovan M, Owen M, et al. The contribution of gene-environment interaction to psychopathology. Dev Psychopathol. 2007;19(4):989–1004.
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  • 8.   Faraone SV, Doyle AE, Mick E, Biederman J. Meta-analysis of the association between the 7-repeat allele of the dopamine D4 receptor gene and attention deficit hyperactivity disorder. Am J Psychiatry. 2001;158(7):1052–7.
  • 9.   Weiss LA, Shen Y, Korn JM, Arking DE, Miller DT, Fossdal R, et al. Association between microdeletion and microduplication at 16p11.2 and autism. N Engl J Med. 2008;358(7):667–75.
  • 10.   Caspi A, Langley K, Milne B, Moffitt TE, O'Donovan M, Owen MJ, et al. A replicated molecular genetic basis for subtyping antisocial behavior in children with attention-deficit/hyperactivity disorder. Arch Gen Psychiatry. 2008;65(2):203–10.
  • 11.   Li D, Sham PC, Owen MJ, He L. Meta-analysis shows significant association between dopamine system genes and attention deficit hyperactivity disorder (ADHD). Hum Mol Genet. 2006;15(14):2276–84.

Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

No conflicts of interest in this work.


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Cite this article

R. Padamavati, P. Sethuraj, P. S. Rathipriya/Studies on Genetic Environment Influences on the Development of Childhood Psychiatric Disorders; A Review/Indian J Trauma Emerg Pediatr.2023;15(2):41–44.


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.



Received Accepted Published
April 17, 2023 May 02, 2023 June 30, 2023

DOI: https://doi.org/10.21088/ijtep.2348.9987.15223.1

Keywords

Adolescent psychiatryChild psychiatricFamily studiesGene environment interactionGene environmentGeneticsMolecular geneticsTwin studies

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Timeline


Received April 17, 2023
Accepted May 02, 2023
Published June 30, 2023

licence


Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.



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