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Correlation of Vitamin D Levels with Cardiac Function in Patients with Dilated Cardiomyopathy

Shreyas Ravat. , Shreyas Ravat , Vikrant Mannikar , Ratan Rathod ,

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Journal of Cardiovascular Medicine and Surgery 6(3):p 195-199, July – September 2020. | DOI: http://dx.doi.org/10.21088/jcms.2454.7123.6320.5

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Shreyas Ravat, Vikrant Mannikar, Ratan Rathod. Correlation of Vitamin D Levels with Cardiac Function in Patients with Dilated Cardiomyopathy. J Cardiovasc Med Surg. 2020;6(3):195-199.
 

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Received : N/A         Accepted : N/A          Published : N/A

Abstract

Introduction: Vitamin D affects immune activation, which is plays a role in the pathogenesis of cardiomyopathy. In the present study we aim to identify correlation between vitamin D levels and echocardiographically determined heart function in patients with dilated cardiomyopathy (DCMP).


Methodology: Cases included patients diagnosed to have DCMP and admitted in our indoor admission ward from January 2019 till December 2019. At the same time, age and gender matched controls were included, which were patients of other medical illnesses admitted in the same hospital. All study participants underwent echocardiography, vitamin D and other biochemical estimations.

Results: During the study period we included 33 cases of DCM and 35 controls. Meanage, gender distribution and BMI was similar for the two study groups. Serum calcium levels were found to be significantly lower in the cases as compared to controls (8.1 ± 1.7 vs 9.8 ± 0.9 mg/dl, p < 0.05). 25(OH)D3 was also found to be significantly lower among cases as compared to controls (13.8 ± 3.2 vs 32.8 ± 6.4 ng/dl, p < 0.01). We observed that the stroke volume, left ventricular ejection fraction and left ventricular fractional shortening had a significant positive correlation with
serum 25 (OH) D3 levels. On the other hand, left ventricular end-diastolic diameter and left ventricular end-systolic diameter had a significant negative correlation with serum 25 (OH) D3 levels.

Conclusions: Our results show that patients with DCMP had lower vitamin D levels than controls, and vitamin D deficiency had a significant correlation with echocardiographic parameters.



 

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Cite this article

Shreyas Ravat, Vikrant Mannikar, Ratan Rathod. Correlation of Vitamin D Levels with Cardiac Function in Patients with Dilated Cardiomyopathy. J Cardiovasc Med Surg. 2020;6(3):195-199.
 

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DOI: http://dx.doi.org/10.21088/jcms.2454.7123.6320.5

Keywords

Vitamin D; Cardiomyopathy; Echocardiography.

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