Home > Journals > Indian Journal of Anesthesia and Analgesia

Indian Journal of Anesthesia and Analgesia

Submit your article Read this Journals View all journals
Full Text (PDF)
Original Article

Comparison of Intravenous Clonidine with Intravenous Lignocaine for Attenuation of Endotracheal Intubation Induced Haemodynamic Response

Rajni Kumari , Rajni Kumari1 , Ajay Kumar2 , Shipra Aggarwal3

Author Information

Licence:



Indian Journal of Anesthesia and Analgesia 6(1):p 349-352, Jan-Feb 2019. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.6119.48

How Cite This Article:

Rajni Kumari, Ajay Kumar, Shipra Aggarwal. Comparison of Intravenous Clonidine with Intravenous Lignocaine for Attenuation of Endotracheal Intubation Induced Haemodynamic Response. Indian J Anesth Analg. 2019;6(1):349-352.

Timeline

Received : N/A         Accepted : N/A          Published : N/A

Abstract

Background: Endotracheal intubation is the standard practice for general anaesthesia inspite of many supraglottic airway devices have arrived. Various drugs have been used till date to attenuate the hemodynamic response to endotracheal intubation. This study compared the effects of intravenous Clonidine (2.5 µg/kg) and Lignocaine (1.5 mg/kg), for attenuation of hemodynamic response in laryngoscopy and endotracheal intubation. Methods: Ninety patients of ASA class I & II were divided into two groups of 45 each. Group L patients received injection Lignocaine and Group C patients received injection Clonidine. Hemodynamic parameters were monitored by using multiparameter monitor before intubation and at 1, 3, 5 and 10 minutes after endotracheal intubation. Results: No significant difference between two groups was observed in terms of hemodynamic parameter including heart rate, systolic blood pressure, diastolic blood pressure and mean arterial pressure. Pretreatment with injection Clonidine is equally better alternative to lignocaine with similar advantages for blunting the undesirable hemodynamic response associated with laryngoscopy and intubation.

References

No records found.


About this article

Cite this article

Rajni Kumari, Ajay Kumar, Shipra Aggarwal. Comparison of Intravenous Clonidine with Intravenous Lignocaine for Attenuation of Endotracheal Intubation Induced Haemodynamic Response. Indian J Anesth Analg. 2019;6(1):349-352.

Licence:



Received Accepted Published
N/A N/A N/A
DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.6119.48

Keywords

Clonidine; Lignocaine; Hemodynamic response; Intubation.

Article Level Metrics

Last Updated

Monday 13 July 2026, 16:36:08 (IST)

5657

Accesses

3
678
00

Citations


NA
NA
NA

Download citation


Article Keywords

Keyword Highlighting

Highlight selected keywords in the article text.


Timeline

Received N/A
Accepted N/A
Published N/A

licence




Access this article

Reprint Order Form
Buy this Article
Institutional Subscriptions

Share