Home > Journals > Indian Journal of Anesthesia and Analgesia

Indian Journal of Anesthesia and Analgesia

Submit your article Read this Journals View all journals
Full Text (PDF)
Original Article

Comparison of Hemodynamic Response Among IV Butorphanol and Dexmedetomidine as a Premedication in Laparoscopic Cholecystectomy

Dheeraj Saxena , Ahmad Waqar Khan1 , Dheeraj Saxena2 , Juhi Saran3 , Geeta Karki4

Author Information

Licence:



Indian Journal of Anesthesia and Analgesia 6(5):p 1715-1721, September-October 2019. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.6519.32

How Cite This Article:

Ahmad Waqar Khan, Dheeraj Saxena, Juhi Saran et al. Comparison of Hemodynamic Response Among IV Butorphanol and Dexmedetomidine as a Premedication in Laparoscopic Cholecystectomy. Indian J Anesth Analg. 2019;6(5 P-II):1715-1721.

Timeline

Received : N/A         Accepted : N/A          Published : N/A

Abstract

Background: In 1940, Reid and Brace first described the hemodynamic response to laryngoscopy and intubation due to noxious stimuli of the upper airway. To minimize this various drugs have been used. Newer opioids like butorphanol, and dexmedetomidine have significant role to suppress hemodynamic changes during laryngoscopy, intubation and pneumoperitoneum. So we have compared the intravenous butorphanol and dexmedetomidine to reduce stress response during laryngoscopy in laparoscopic cholecystectomy. Materials and Methods: The study was carried on 100 patients of both sex with comparable characteristics and of ASA Grade I and II physical status. Patients were allocated into two groups: Group B inj. Butorphanol 30 μg/kg was given 5 minutes before induction and Group D inj. Dexmedetomidine 1 μg/kg diluted in 10 ml normal saline, was given in 10 minutes by infusion pump. Results: The rise in heart rate and blood pressure was less in Dexmedetomidine group as compared to Butorphanol. Conclusions: Dexmedetomidine is better in attenuating the stress response during laryngoscopy, intubation and pneumoperitoneum as compared to butorphanol.

References

No records found.


About this article

Cite this article

Ahmad Waqar Khan, Dheeraj Saxena, Juhi Saran et al. Comparison of Hemodynamic Response Among IV Butorphanol and Dexmedetomidine as a Premedication in Laparoscopic Cholecystectomy. Indian J Anesth Analg. 2019;6(5 P-II):1715-1721.

Licence:



Received Accepted Published
N/A N/A N/A
DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.6519.32

Keywords

Dexmedetomidine; Butorphanol; Laparoscopic Cholecystectomy; hemodynamic response; pneumoperitoneum; laryngoscopy.

Article Level Metrics

Last Updated

Saturday 28 February 2026, 16:43:25 (IST)

1389

Accesses

0
245
00

Citations


NA
NA
NA

Download citation


Article Keywords

Keyword Highlighting

Highlight selected keywords in the article text.


Timeline

Received N/A
Accepted N/A
Published N/A

licence




Access this article

Reprint Order Form
Buy this Article
Institutional Subscriptions

Share