Full Text (PDF)
Indian Journal of Anesthesia and Analgesia 6(2):p 379-386, MARCH-APRIL 2019. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.6219.2
Original Article
Comparision of Intrathecal Fentanyl and Clonidine with 0.5% of Bupivacaine Heavy in Spinal Anaesthesia in Elderly Urological Surgeries
Amarjeet D. Pati , Amarjeet D. Patil1# , Vennel Jessy2 , Bhumika Kathiriya3
Author Information
Licence:
Indian Journal of Anesthesia and Analgesia 6(2):p 379-386, MARCH-APRIL 2019. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.6219.2
How Cite This Article:
Amarjeet D. Patil, Vennel Jessy, Bhumika Kathiriya. Comparision of Intrathecal Fentanyl and Clonidine with 0.5% of Bupivacaine Heavy in Spinal Anaesthesia in Elderly Urological Surgeries. Indian J Anesth Analg. 2019;6(2):379-385.
Timeline
Received : N/A
Accepted : N/A
Published : N/A
Abstract
Background: Lipophilic opioids (fentanyl) and alpha-2 agonist (clonidine) are increasingly being administered intrathecally as adjuncts. They enhance the effect of spinal anaesthesia without prolonging motor recovery and discharge time. Aims and objectives: To work out the influence of intrathecal fentanyl vs intrathecal clonidine with low dose (2.5 ml) bupivacaine in urological surgeries. Materials and methods: The study was a randomized, prospective study conductedas a double blind trial at the tertiary care hospital. Total 60 patients were included in this study, after fulfilling standard criteria. The study population have patients of either sex, ASA physical status I and II in the range of 50-70 years. Patients were randomly assigned to Fentanyl (F)group and Clonidine (C) group. They were assessed for analgesia time, complications, hemodynamic changes and sensory and motor block. Statistical tests: All the data was collected and entered in Microsoft Excel sheet and transferred to SPSS software ver.17 for analysis. Chi-Square test, unpaired student ‘t’ test and paired ‘t’ test wasused. P - Value of <0.05 was considered statistically significant and that of < 0.001 was considered statistically highly significant. Results: Time of onset of motor block (min) was significantly faster in group C (2.21 ± 0.6) as compared to group F (5.4 ± 0.8). Time of onset of sensory block (min) was significantly faster in group C (2.44 ± 0.5) as compared to group F (6.12 ± 0.7). Conclusion: The onset of sensory and motor blockade was faster with clonidine. Clonidine offered good post-operative analgesia. Fentanyl may be a better choice for surgeries requiring minimal hospital stay.
References
No records found.
About this article
Cite this article
Amarjeet D. Patil, Vennel Jessy, Bhumika Kathiriya. Comparision of Intrathecal Fentanyl and Clonidine with 0.5% of Bupivacaine Heavy in Spinal Anaesthesia in Elderly Urological Surgeries. Indian J Anesth Analg. 2019;6(2):379-385.
Licence:
| Received | Accepted | Published |
|---|---|---|
| N/A | N/A | N/A |
DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.6219.2
Keywords
Intrathecal AnaesthesiaBupivacaineFentanylClonidineUrologicalSurgeries.Search for Similar Articles
Similar Articles
- Anesthetic Management of a Two-Year-Old Child with Mucolipidosis using the I-gel...
- Ephemeral Tachyarrhythmia During Laparoscopy: An Enigma
- Threading the Needle between Clots and Grafts: Anaesthetic Challenges for Urgent...
- Tachyarrhythmia Ventricular Tachycardia Following Injection Neostigmine: A Rare...
- A Case of Persistent Atrial Fibrillation for Laparoscopic Cholecystectomy
Article Level Metrics
Last UpdatedSaturday 07 February 2026, 21:13:44 (IST)
1189
Accesses
1
194
00
Citations
NA
NA
NA
Download citation
Article Keywords
Keyword Highlighting
Highlight selected keywords in the article text.
Timeline
| Received | N/A |
| Accepted | N/A |
| Published | N/A |