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Cholesterol Reducing Drugs and its Effect on the Level of CoQ10

Sachin C. Narwadiya, Scientist C., Vigyan Prasar, A50, Institutional Area, Sector 62,Noida201309. , Sachin C. Narwadiya

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RFP Journal of Biochemistry and Biophysics 2(1):p 53-57, January - June 2017. | DOI:

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Abstract

The cholesterol lowering drugs are becoming popular among the society. As the society is suffering from obesity due to disturbed life style and increasing fast food habits. The Coenzyme Q10 also termed as CoQ10 is located in the mitochondria of eukaryotic cells. It has the property of solubility in oil and it’s like vitamin. The CoQ10 plays and important role in cellular respiration specifically in electron transport chain. The CoQ10 reactions results into the generation of Adenosine TriPhosphate (ATP). The maximum amount of energy of the body needs generated through this way. The organs having more energy requirements like heart, liver, kidneys have the elevated levels of CoQ10. It is evident that the cholesterol level reducing drugs also critically reduces the CoQ10 . The reduction of the CoQ10 level further shows adverse effects. The biosynthesis of cholesterol and CoQ10 has same point during the pathway. The therapy needs more indepth research. The consideration and recognition of a drug as cholesterol level reducing drug will have more critical trials. The society will be really benefited if the drug is safe and have minimum or no side effects.

Keywords: Adenosine TriphosphateATP; CoEnzyme Q10; Cholesterol Lowering Drugs; Obesity. 

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