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Changes in left Ventricular Function after Double valve Replacement for Combined Aortic and Mitral valve Diseases

Divya Mallikarjun, Assistant Professor, Department of Cardiothoracic and Vascular Surgery, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bangalore, Karnataka 560069, India , Divya Mallikarjun , Giridhar Kamalapurkar , Anand Kuriyan Mathew3

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Journal of Cardiovascular Medicine and Surgery 4(3):p 211-216, Jul-Sep 2018. | DOI: http://dx.doi.org/10.21088/jcms.2454.7123.4318.3

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Abstract

Context: Rheumatic disease is the most common cause in our country. Few data are available on post operative left ventricular function in patients with mixed stenotic and regurgitant lesions. In this study, we sought to analyze short term changes in LV function after DVR in combined rheumatic and mitral diseases. Aim: To analyze the short term changes in LV function after DVR in combined rheumatic aortic and mitral diseases. Settings and Design: Prospective analysis of all cases of DVR in combined rheumatic aortic and mitral diseases done from 1/8/2012 to 31/12/2013 in 2 surgical units at Sri Jayadeva Institute of Cardiovascular Sciences and Research and their serial clinical and 2-D Trans Thoracic Echocardiographic evaluations, post-operatively, for 1 year. Methods and Material: Serial clinical and echocardiographic evaluations were performed prospectively in patients who underwent double valve replacement for combined aortic and mitral valve diseases, immediate post-operatively, at 3 months and at 1 year. For purposes of comparison, 2 groups were made based on types of lesions, i.e. purely regurgitant lesions and combined stenotic and regurgitant lesions. Statistical analysis used: Data are presented as mean ±SD. Group comparisons made by the use of Paired t test. Significance assumed at a two-tailed value of p<0.05. Results: Left ventricular diastolic and systolic dimensions and volumes reduced significantly at 3 months in regurgitant group but not in the mixed lesions group. Conclusions: In patients with NYHA class upto III with severely dilated left ventricle and low ejection fraction, double valve replacement surgery can be done safely.

 

 

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DOI: http://dx.doi.org/10.21088/jcms.2454.7123.4318.3

Keywords

LV Function; DVR; Mixed Lesions

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