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Case Report

Biphenotypic Sinonasal Sarcoma: A Rare Case Report

Virendra bhandari null, Pragati Kesharwani1 null, Somya Sharma2 null, Saloni Singhal3 null, Ashar Iqbal Lodi4 null, Virendra Bhandari5 null

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Indian Journal of Cancer Education and Research 12(1):p 27-30, January - June 2024. | DOI: https://doi.org/10.21088/ijcer.2321.9815.12124.4

How Cite This Article:

Pragati Kesharwani, Somya Sharma, Saloni Singhal et. al. Biphenotypic Sinonasal Sarcoma: A Rare Case Report/Ind J Canc Educ  Res 2024;12(1):27-30.
 

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Received : January 05, 2024         Accepted : January 15, 2024          Published : March 15, 2024

Abstract

Background: Biphenotypic Sinonasal Sarcoma (BSNS) is a recently described tumor with
its site of origin limited to the nose and paranasal sinus. It is a rare low-grade sarcoma
characterized by concomitant neural and myogenic differentiation with high recurrence rates
but lacks metastatic potential. Limited literature is available about the standard treatment
regimens due to their rarity.
Case Presentation: Herein we describe the details of the case of a 55-year-old male,
known case of recurrent biphenotypic sinonasal Sarcoma who presented with bilateral nasal
obstruction. The diagnosis was confirmed by immunohistochemistry. He underwent surgery
but developed recurrence twice, and later treated with Radiation Therapy.
Conclusions: Mainstay of the treatment remains surgery but due to its rarity, no definite
treatment guidelines are defined. Radica or adjuvant treatment with chemotherapy and/or
radiotherapy have been tried with limited data on the outcome.
 

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Cite this article

Pragati Kesharwani, Somya Sharma, Saloni Singhal et. al. Biphenotypic Sinonasal Sarcoma: A Rare Case Report/Ind J Canc Educ  Res 2024;12(1):27-30.
 

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Received Accepted Published
January 05, 2024 January 15, 2024 March 15, 2024
DOI: https://doi.org/10.21088/ijcer.2321.9815.12124.4

Keywords

Biphenotypic Sinonasal Sarcoma; Spindle Cell Neoplasm; SMA; PAX3

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Timeline

Received January 05, 2024
Accepted January 15, 2024
Published March 15, 2024

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