Abstract

Thermal burns are a common cause of mixed second burn injuries, often associated with pain, frequent dressing changes, and delayed epithelialization. Biocellulose dressings have emerged as advanced wound care materials due to their moistureretentive, biocompatible, and analgesic properties

• 1.   Fu L, Zhang J, Yang G. Present status and applications of bacterial cellulose-based materials for skin tissue repair. Carbohydr Polym. 2013; 92(2): 1432-42.
• 2.   Czaja W., Krystynowicz A., Bielecki S., Brown R.M. Microbial cellulose—the natural power to heal wounds. Biomaterials. 2006; 27(2): 145-51.
• 3.   Alvarez G.S., Moreira F.F., Ponce L., KogaIto C.Y., Popat K.C., Matsumoto T. Advances in biocellulose-based materials for wound healing. Adv Healthc Mater. 2020; 9(15): 2000734.
• 4.   Picheth G.F., Pirich C.L., Sierakowski MR, Woehl M.A., Sakakibara C.N., de Souza C.F., et al. Bacterial cellulose in biomedical applications: a review. Int J Biol Macromol. 2017; 104(Pt A): 97-106.
• 5.   Ardor Biomed India Pvt Ltd. Cocoheal® biocellulose wound dressing: product information leaflet. Coimbatore (India): Ardor Biomed India Pvt Ltd; 2025.
• 6.   Mayrand D., Samson L., Hélie P., Vincent C., Mottard S., Guertin L.. Clinical evaluation of a microbial cellulose wound dressing in the management of second-degree burns. J Burn Care Res. 2012; 33(3): e110-7.
• 7.   Zajicek R., Matejovic T., Koller J., Vistejnova L., Suchanek J., Stiborova I., et al. Comparison of microbial cellulose and silver-impregnated dressings in the treatment of superficial partialthickness burns. Burns. 2019; 45(1): 146-52.
• 8.   Revin V.V., Liyaskina E.V., Nazarkina Y.V., Bogatyreva A.O., Shchankin M.A. Bacterial cellulose and its applications in biomedicine and cosmetics. Polymers (Basel). 2018; 10 (3): 347.
• 9.   Czaja WK, Young DJ, Kawecki M, Brown RM. The future prospects of microbial cellulose in biomedical applications. Biomacromolecules. 2007; 8(1): 1-12.
• 10.   Huang Y., Zhu C., Yang J., Nie Y., Chen C., Sun D. Recent advances in bacterial cellulose for biomedical applications. Int J Biol Macromol. 2014; 66: 166-74.
• 11.   Wichai S., Chuysinuan P., Chaiarwut S., Ekabutr P., Supaphol P. Development of bacterial cellulose/alginate/chitosan composite sponges for wound dressing applications. Int J Biol Macromol. 2019; 131: 1090-100.
• 12.   Ardor Biomed India Pvt Ltd. Cocoheal® biocellulose wound dressing [Internet]. Coimbatore (India): Ardor Biomed India Pvt Ltd; c2025 [cited 2026 Feb 5]. Available from: manufacturer’s website.

Data Sharing Statement

Funding