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Antimicrobial Efficacy of Nanoparticles Loaded with Herbal Extracts on Polyester/Cotton Blend Fabrics in Combating Nosocomial Infection

C. Geethadevi, R. Rajendran, R. Radhai, Dhanya Subraminam

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Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

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RFP Indian Journal of Hospital Infection 1(1):p 5-13, January-June 2024. | DOI: NA

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Timeline

Received : February 05, 2024         Accepted : April 28, 2024          Published : June 21, 2024

Abstract

A nosocomial or hospital acquired infection is an infection which a patient develops during hospitalization. Contaminated textiles in hospitals might be an important source of microbes contributing to endogenous, indirectcontact, and aerosol transmission of nosocomialrelated pathogens. Textiles are an excellent substrate for bacterial and fungal growth under appropriate moisture and temperature conditions. The use of antimicrobial textiles, especially in those that are in close contact with the patients, may appreciably reduce bio burden in clinical settings and consequently reduce the risk of nosocomial infection. In view of increasing resistance to existing antimicrobial agents, herbal drugs are being looked as very important source for the discovery of new agents for treating various ailments related to bacterial infections. Nanotechnology has real commercial potential for the textile industry. This is mainly due to the fact that conventional methods used to impart different properties to fabrics often do not lead to permanent effects, and will lose their functions after laundering or wearing. Nanotechnology can provide high durability for fabrics, because nanoparticles have a large surface areatovolume ratio and high surface energy, thus presenting better affinity for fabrics and leading to an increase in durability of the function. The study dealt with imparting antimicrobial property to polyester / cotton blend fabrics using nanoparticles loaded withcombinatorial herbal extracts and its efficacywas evaluated in a hospital environment. The results proved that the load of microorganisms was comparatively lesser than the control fabrics, this shows that these fabrics could control the transmission of nosocomial infection through fomites.


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Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

No conflicts of interest in this work.


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Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


Received Accepted Published
February 05, 2024 April 28, 2024 June 21, 2024

DOI: NA

Keywords

Nosocomial InfectionHerbal Nanoparticles;Polycotton Fabrics;Antimicrobial Textiles

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Received February 05, 2024
Accepted April 28, 2024
Published June 21, 2024

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Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


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